Protein Information

General Information
MoonProt ID171
First appeared in release1.0
Name(s)60S ribosomal protein L13a 23 kDa highly basic protein Gene Name: RPL13A
UniProt IDP40429 (RL13A_HUMAN), Reviewed
GO termsGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0006412 translation GO:0006413 translational initiation GO:0006414 translational elongation GO:0006415 translational termination GO:0006417 regulation of translation GO:0006614 SRP-dependent cotranslational protein targeting to membrane GO:0010467 gene expression GO:0016032 viral process GO:0016070 RNA metabolic process GO:0016071 mRNA metabolic process GO:0017148 negative regulation of translation GO:0019058 viral life cycle GO:0019083 viral transcription GO:0044267 cellular protein metabolic process GO:0071346 cellular response to interferon-gamma GO:1901194 negative regulation of formation of translation preinitiation complex GO:0003735 structural constituent of ribosome GO:0044822 poly(A) RNA binding GO:0005737 cytoplasm GO:0005829 cytosol GO:0005840 ribosome GO:0015934 large ribosomal subunit GO:0022625 cytosolic large ribosomal subunit GO:0030529 ribonucleoprotein complex GO:0097452 GAIT complex
Organisms for which functions have been demonstratedHomo sapien
Sequence length203
FASTA sequence>sp|P40429|RL13A_HUMAN 60S ribosomal protein L13a OS=Homo sapiens GN=RPL13A PE=1 SV=2 MAEVQVLVLDGRGHLLGRLAAIVAKQVLLGRKVVVVRCEGINISGNFYRNKLKYLAFLRKRMNTNPSRGPYHFRAPSRIFWRTVRGMLPHKTKRGQAALDRLKVFDGIPPPYDKKKRMVVPAALKVVRLKPTRKFAYLGRLAHEVGWKYQAVTATLEEKRKEKAKIHYRKKKQLMRLRKQAEKNVEKKIDKYTEVLKTHGLLV
Structure Information
PDB ID3J3B
Quaternary structure
Function 1
Function descriptionribosome protein, part of 60S subunit of ribosome
References for function
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasem, part of ribosome
Comments
Function 2
Function descriptiontranslation inhibition Component of the GAIT complex (gamma interferon-activated inhibitor of translation)
References for functionMazumder B, Sampath P, Seshadri V, Maitra RK, DiCorleto PE, Fox PL. Regulated release of L13a from the 60S ribosomal subunit as a mechanism of transcript-specific translational control. Cell. 2003 Oct 17. PMID: 14567916
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasm
Comments