Protein Information

General Information
MoonProt ID177
First appeared in release1.0
Name(s)60S ribosomal protein L10 Laminin receptor homolog Protein QM Tumor suppressor QM Gene Name: RPL10
UniProt IDP27635 (RL10_HUMAN), Reviewed
GO termsGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0006412 translation GO:0006413 translational initiation GO:0006414 translational elongation GO:0006415 translational termination GO:0006614 SRP-dependent cotranslational protein targeting to membrane GO:0010467 gene expression GO:0016032 viral process GO:0016070 RNA metabolic process GO:0019058 viral life cycle GO:0019083 viral transcription GO:0044267 cellular protein metabolic process GO:0003735 structural constituent of ribosome GO:0005515 protein binding GO:0044822 poly(A) RNA binding GO:0005622 intracellular GO:0005783 endoplasmic reticulum GO:0005829 cytosol GO:0005840 ribosome GO:0022625 cytosolic large ribosomal subunit GO:0030529 ribonucleoprotein complex
Organisms for which functions have been demonstratedHomo sapiens
Sequence length214
FASTA sequence>sp|P27635|RL10_HUMAN 60S ribosomal protein L10 OS=Homo sapiens GN=RPL10 PE=1 SV=4 MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVDEFPLCGHMVSDEYEQLSSEALEAARICANKYMVKSCGKDGFHIRVRLHPFHVIRINKMLSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNKEHVIEALRRAKFKFPGRQKIHISKKWGFTKFNADEFEDMVAEKRLIPDGCGVKYIPNRGPLDKWRALHS
Structure Information
PDB ID2ZKR, 3J3B
Quaternary structure
Function 1
Function descriptionComponent of the large subunit (60S) of the ribosome
References for function
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasm, part of ribosome
Comments
Function 2
Function descriptionnegative regulator of c-Jun in transcription
References for functionImafuku I, Masaki T, Waragai M, Takeuchi S, Kawabata M, Hirai S, Ohno S, Nee LE, Lippa CF, Kanazawa I, Imagawa M, Okazawa H. Presenilin 1 suppresses the function of c-Jun homodimers via interaction with QM/Jif-1. J Cell Biol. 1999 Oct 4. PMID: 10508860
E.C. numberN/A
Location of functional site(s)
Cellular location of functionnucleus
Comments