Protein Information

General Information
MoonProt ID18
First appeared in release1.0
Name(s)Chaperone protein DnaK HSP70 Heat shock 70 kDa protein Heat shock protein 70 Gene Name:dnaK
UniProt IDQ8G6W1 (DNAK_BIFLO), Reviewed
GO termsGO:0006457 protein folding GO:0006950 response to stress GO:0000166 nucleotide binding GO:0005524 ATP binding GO:0051082 unfolded protein binding
Organisms for which functions have been demonstratedBifidobacterium(Bifidobacterium lactis, B. bifidum, and B. longum) (Gram positive bacterium)
Sequence length581
FASTA sequence>sp|Q8G6W1|DNAK_BIFLO Chaperone protein DnaK OS=Bifidobacterium longum (strain NCC 2705) GN=dnaK PE=3 SV=1 MARAVGIDLGTTNSCIATLEGGEPTVIVNAEGARTTPSVVAFSKSGEILVGEVAKRQAVTNVDRTISSVKRHMGSDWTVDIDGKKWTPQEISAQILMKLKRDAEAYLGEPVTDAVITCPAYFNDAQRQATKDAGKIAGLNVLRIINEPTAAALAYGLEKGKEDERILVFDLGGGTFDVSLLEIGKDDDGFSTIQVQATNGDNHLGGDDWDQKIIDWLVSEVKNKYGVDLSKDKIALQRLKEAAEQAKKELSSSTSTSISMQYLAMTPDGTPVHLDETLTRAHFEEMTSDLLGRCRTPFNNVLHDAGISVSDIDHVVLVGGSTRMPAVKELVKELTGGKEANQSVNPDEVVAVGAAVQSGVIKGDRKDVLLIDVTPLSLGIETKGGIMTKLIDRNTAIPTKRSEVFSTAEDNQPSVLIQVYQGEREFARDNKPLGTFELTGIAPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGKEQSMTITGGSGLPKDEIDRMVKEAEAHEAEDKKRKEDAETRNQAEAFAYSTEKLVNDNKDKLSDDIVKEVTDKVNALKEALKGDDTEKVKTAQTELMTAAQKIGQVLYAQQGAEGAAAGADGAGASAGSASGSDDDTVEAEVVDDDDDKDNK
Structure Information
PDB IDClosest homologue is 4RTF_A (73.41%)
Quaternary structure
SCOPNA
CATHNA
TM Helix Predictionno TM helices
DisProt AnnotationNot in DisProt
Predicted Disorder Regions1-2,248-251,475-488,495-515,531-538,558-562,583-610,617-626
Connections to Disease
OMIM ID
Function 1
Function descriptionchaperone
References for function
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionplasminogen binding
References for functionCandela M, et al. 2007. Binding of human plasminogen to Bifidobacterium. J. Bacteriol.2007 Aug;189(16):5929-36. Epub 2007 Jun 8.PMID:17557824
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell wall
Comments