| General Information |
| MoonProt ID | 18 |
| First appeared in release | 1.0 |
| Name(s) | Chaperone protein DnaK
HSP70
Heat shock 70 kDa protein
Heat shock protein 70
Gene Name:dnaK
|
| UniProt ID | Q8G6W1 (DNAK_BIFLO), Reviewed |
| GO terms | GO:0006457 protein folding
GO:0006950 response to stress
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0051082 unfolded protein binding |
| Organisms for which functions have been demonstrated | Bifidobacterium(Bifidobacterium lactis, B. bifidum, and B. longum) (Gram positive bacterium) |
| Sequence length | 581 |
| FASTA sequence | >sp|Q8G6W1|DNAK_BIFLO Chaperone protein DnaK OS=Bifidobacterium longum (strain NCC 2705) GN=dnaK PE=3 SV=1
MARAVGIDLGTTNSCIATLEGGEPTVIVNAEGARTTPSVVAFSKSGEILVGEVAKRQAVTNVDRTISSVKRHMGSDWTVDIDGKKWTPQEISAQILMKLKRDAEAYLGEPVTDAVITCPAYFNDAQRQATKDAGKIAGLNVLRIINEPTAAALAYGLEKGKEDERILVFDLGGGTFDVSLLEIGKDDDGFSTIQVQATNGDNHLGGDDWDQKIIDWLVSEVKNKYGVDLSKDKIALQRLKEAAEQAKKELSSSTSTSISMQYLAMTPDGTPVHLDETLTRAHFEEMTSDLLGRCRTPFNNVLHDAGISVSDIDHVVLVGGSTRMPAVKELVKELTGGKEANQSVNPDEVVAVGAAVQSGVIKGDRKDVLLIDVTPLSLGIETKGGIMTKLIDRNTAIPTKRSEVFSTAEDNQPSVLIQVYQGEREFARDNKPLGTFELTGIAPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGKEQSMTITGGSGLPKDEIDRMVKEAEAHEAEDKKRKEDAETRNQAEAFAYSTEKLVNDNKDKLSDDIVKEVTDKVNALKEALKGDDTEKVKTAQTELMTAAQKIGQVLYAQQGAEGAAAGADGAGASAGSASGSDDDTVEAEVVDDDDDKDNK
|
| Structure Information |
| PDB ID | Closest homologue is 4RTF_A (73.41%) |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1-2,248-251,475-488,495-515,531-538,558-562,583-610,617-626 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | chaperone |
| References for function | |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | plasminogen binding |
| References for function | Candela M, et al. 2007. Binding of human plasminogen to Bifidobacterium. J. Bacteriol.2007 Aug;189(16):5929-36. Epub 2007 Jun 8.PMID:17557824 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cell wall |
| Comments | |