General Information |
MoonProt ID | 202 |
First appeared in release | 1.0 |
Name(s) | O-GlcNAc transferase
glycosyl transferase
Gene Name:gmaR |
UniProt ID | A0A0E0UUG2 |
GO terms | GO:0008152 metabolic process
GO:0016740 transferase activity |
Organisms for which functions have been demonstrated | Listeria monocytogenes (Gram positive bacterium, causes listeriosis, septicemia, meningitis) |
Sequence length | 637 aa |
FASTA sequence | >tr|F8BDH3|F8BDH3_LISMM Putative glycosyl transferases flagella synthesis antirepressor OS=Listeria monocytogenes serotype 4a (strain M7) GN=gmaR PE=4 SV=1
MRPLISICMIVKNEAHILRQSLASFRKFTEEIIIVDTGSTDETKEIAQEFTDFVYDFEWTGNFSDARNFAAKHATGKWILAIDADECLEEESYRKLEKQLKSPIEPIQMAQIISFTGEKGRVTTTNQMARVYKNDGTICFRGVIHEQLEAVDKHPIAAGVAEVKIYHYGYMTEIVEKQDKSDRNLRLLEKEVKNNKNSGFVHFNIGQEMNRLGNKKEALKEFSEAFRLRDHNHYIWAKLSAYHIAELLEQEKRYDESLAIIEEARIIWPNVPEFPLKKANILYVNHQLEDAKEIYQSLLENTAIDYQPIVLYEATNFMPHKMLGTIYLEEKDYTRAMTHFSKAYAENSSDYGVMFQMIMLLSKFHQPKEIFAFMERHHFISSTETGLRLLSMTTQQGYAELSELIVQSLTDVYPPVAEATEVKIATIRNVFPVISESAILFGIKEELIDAADLCLWHYENPQLPIERVMKNSDVGDIYDFIFENGPRISKKRYLFVLERAIALGKGEFADYLLALRNVYHDSINSHIADLFFQYDFADIALDFYNIVDADEVTKQGYINLINYLVDAEVLDEALAIAERGIDNFSTDFRFYLWTIKIDTENRANRISEAMDEFPNNRYLAKLLDEVTMLQDTVTNNR
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Structure Information |
PDB ID | None |
Quaternary structure | |
SCOP | NA |
CATH | NA |
TM Helix Prediction | no TM helices |
DisProt Annotation | Not in DisProt |
Predicted Disorder Regions | 1, 630-637 |
Connections to Disease |
OMIM ID | |
Function 1 |
Function description | O-GlcNAc transferase
glycosyltransferase that mediates beta-O-linked GlcNAc modification of flagellin (FlaA) |
References for function | Shen A, Kamp HD, Gr?ndling A, Higgins DE. A bifunctional O-GlcNAc transferase governs flagellar motility through anti-repression. Genes Dev. 2006 Dec 1. PMID: 17158746 |
E.C. number | 2.4.1.255 |
Location of functional site(s) | |
Cellular location of function | cytoplasm |
Comments | |
Function 2 |
Function description | transcriptional regulator
anti-repressor, target is MogR (a transcriptional repressor), binds to MogR and prevents it from binding to DNA |
References for function | Shen A, Kamp HD, Gr?ndling A, Higgins DE. A bifunctional O-GlcNAc transferase governs flagellar motility through anti-repression. Genes Dev. 2006 Dec 1. PMID: 17158746 |
E.C. number | N/A |
Location of functional site(s) | |
Cellular location of function | cytoplasm |
Comments | |