| General Information |
| MoonProt ID | 269 |
| First appeared in release | 1.0 |
| Name(s) | 50S ribosomal protein L14
Rep helicase stimulatory protein
RHSP
Gene Name:rplN |
| UniProt ID | P0ADY3 (RL14_ECOLI), Reviewed |
| GO terms | GO:0006412 translation
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0019843 rRNA binding
GO:0070180 LSU rRNA binding
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:0030529 ribonucleoprotein complex |
| Organisms for which functions have been demonstrated | Escherichia coli (Gram negative bacterium) |
| Sequence length | 123 |
| FASTA sequence | >sp|P0ADY3|RL14_ECOLI 50S ribosomal protein L14 OS=Escherichia coli (strain K12) GN=rplN PE=1 SV=1
MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIKEAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGPVTRELRSEKFMKIISLAPEVL
|
| Structure Information |
| PDB ID | 1P86,
2AW4,
2AWB,
1VS6,
1VS8,
2I2T,
2I2V,
2QOV, 2QOX,
2QOZ,
2QP1,
2QAM,
2QAO,
2QBA,
2QBC,
1P85,
3OFQ,
3OFR,
3OFC,
3OFD,
3OFZ,
3OG0,
3OAS,
3OAT,
3R8S,
3R8T,
3J19,
3J5L, 3J50,
3J51,
3J52,
3J54,
3J56,
3J58,
3J5A,
3J5C,
3J5E,
3J5G,
3J5I,
3J5K, 3J4X,
2GYA,
2GY |
| Quaternary structure | |
| SCOP | |
| CATH | |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1-2 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | ribosomal protein
part of the 30S subunit
binds to the 23S rRNA
|
| References for function | |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm, part of ribosome |
| Comments | |
| Function 2 |
| Function description | binds DNA
stimulates unwinding of DNA by Rep helicase protein
|
| References for function | Yancey JE, Matson SW. The DNA unwinding reaction catalyzed by Rep protein is facilitated by an RHSP-DNA interaction. Nucleic Acids Res. 1991 Jul 25;19(14):3943-51.
PMID: 1650456 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm, bound to DNA |
| Comments | |