Protein Information

General Information
MoonProt ID303
First appeared in release2.0
Name(s)aldolase, fructose-1,6-bisphosphate aldolase, fructose-bisphosphate aldolase, Gene: LDBPK_361320
UniProt IDE9BTJ1 (E9BTJ1_LEIDB)
GO termsGO:0006096 glycolytic process GO:0003824 catalytic activity GO:0004332 fructose-bisphosphate aldolase activity GO:0016829 lyase activity
Organisms for which functions have been demonstrated
Sequence length371 amino acids
FASTA sequence>tr|E9BTJ1|E9BTJ1_LEIDB Fructose-bisphosphate aldolase OS=Leishmania donovani (strain BPK282A1) GN=LDBPK_361320 PE=3 SV=1 MSRVTIFQSQLPACNRLKTPYESELIATVKKLTTPGKGLLAADESIGSCTKRFEPIGLSNTEEHRRQYRALMLEAEGFEQYISGVILHEETVGQKASNGQTFPEYLTARGVVPGIKTDMGLCPLLEGAEGEQMTEGLDGYVKRASAYYKKGCRFCKWRNVYKIQNGTVSESAVRFNAETLARYAILSQISGLVPIVEPEVMIDGKHDIDTCQRVSEHVWREVVAALQRHGVIWEGCLLKPNMVVPGAESGQTAAPAQVAHYTVMTLARTMPAMLPGVMFLSGGLSEVQASEYLNAINNSPLPRPYFLSFSYARALQSSALKAWGGKDSGVAAGRRAFLHRARMNSMAQLGKYKRADDDASSSSLYVKGNTY
Structure Information
PDB IDNone, but structures available from L. mexicana aldolase
Quaternary structure
Function 1
Function descriptionaldolase, cleavage of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate, in glycolysis
References for function
E.C. number4.1.2.13
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionActivation of mouse (host) macrophage protein tyrosine phosphatase-1 (SHP-1), causes macrophage disfunction
References for function
E.C. number
Location of functional site(s)
Cellular location of functionsecreted
Comments