General Information |
MoonProt ID | 321 |
First appeared in release | 2.0 |
Name(s) | elongation factor 1alpha, EF-1alpha, Elongation factor 1-alpha 1, EF-1-alpha-1, Elongation factor Tu, EF-Tu, Eukaryotic elongation factor 1 A-1, eEF1A-1, Gene: EEF1A1 |
UniProt ID | P68105 (EF1A1_RABIT) |
GO terms | GO:0006412 translation
GO:0006414 translational elongation
GO:0071364 cellular response to epidermal growth factor stimulus
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0019001 guanyl nucleotide binding
GO:0019901 protein kinase binding
GO:0044822 poly(A) RNA binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005730 nucleolus |
Organisms for which functions have been demonstrated | Oryctolagus cuniculus (rabbit) |
Sequence length | 462 amino acids |
FASTA sequence | >sp|P68105|EF1A1_RABIT Elongation factor 1-alpha 1 OS=Oryctolagus cuniculus GN=EEF1A1 PE=1 SV=1
MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETSKYYVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTLLEALDCILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGVLKPGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRGNVAGDSKNDPPMEAAGFTAQVIILNHPGQISAGYAPVLDCHTAHIACKFAELKEKIDRRSGKKLEDGPKFLKSGDAAIVDMVPGKPMCVESFSDYPP |
Structure Information |
PDB ID | 4C0S_A, 92.19% similarity to Chain A, Elongation Factor 1-alpha 2 [Oryctolagus cuniculus] |
Quaternary structure | |
SCOP | NA |
CATH | NA |
TM Helix Prediction | no TM helices |
DisProt Annotation | Not in DisProt |
Predicted Disorder Regions | 1-7, 128-129, 223, 325-333, 383-390, 445-462 |
Connections to Disease |
OMIM ID | |
Function 1 |
Function description | translation elongation factor |
References for function | |
E.C. number | |
Location of functional site(s) | |
Cellular location of function | cytoplasm |
Comments | |
Function 2 |
Function description | binds and severs microtubules |
References for function | 7939665 |
E.C. number | |
Location of functional site(s) | |
Cellular location of function | cytoplasm |
Comments | |