| General Information |
| MoonProt ID | 329 |
| First appeared in release | 2.0 |
| Name(s) | endopeptidase O, PepO, Gene: pepO |
| UniProt ID | Q8DNW9 (Q8DNW9_STRR6) |
| GO terms | GO:0006508 proteolysis
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0016787 hydrolase activity |
| Organisms for which functions have been demonstrated | Streptococcus pneumoniae (Gram positive bacterium) |
| Sequence length | 630 amino acids |
| FASTA sequence | >tr|Q8DNW9|Q8DNW9_STRR6 Endopeptidase O OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) GN=pepO PE=4 SV=1
MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLMLATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADFTAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELLTLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYEDFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEESWSLLKATLILSVVNLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSPEAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKDKVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFPAAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAAFKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFYNFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPEERVIIW |
| Structure Information |
| PDB ID | |
| Quaternary structure | |
| SCOP | |
| CATH | |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 49-56 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | endopeptidase, metalloendopeptidase |
| References for function | |
| E.C. number | 3.4.24.- |
| Location of functional site(s) | |
| Cellular location of function | |
| Comments | |
| Function 2 |
| Function description | plasminogen binding protein, fibronectin binding protein |
| References for function | 23341464 |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |