General Information |
MoonProt ID | 346 |
First appeared in release | 2.0 |
Name(s) | GAPDH, glyceraldehyde 3-phosphage dehydrogenase, glyceraldehyde-3-phosphgae dehydrogenase, Gene: gapdh |
UniProt ID | A8C5S7 (A8C5S7_TALMA) |
GO terms | GO:0006006 glucose metabolic process
GO:0006096 glycolytic process
GO:0055114 oxidation-reduction process
GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding |
Organisms for which functions have been demonstrated | Talaromyces marneffei (Penicillium marneffei) |
Sequence length | 337 amino acids |
FASTA sequence | >tr|A8C5S7|A8C5S7_TALMA Glyceraldehyde-3-phosphate dehydrogenase OS=Talaromyces marneffei GN=gapdh PE=2 SV=1
MVTKVGINGFGRIGRIVFRNVIEHDDAEVVAVNDPFIETHYAAYMLKYDTQHGQFKGTIEVEGSDLIVNGKRVKFYQERDPANIKWSETGAAYIVESTGVFTTTEKASAHLKGGAKKVVISAPSADAPMFVMGVNHTTYKSSDTIISNASCTTNCLAPLAKIVNDNWGLVEGLMTTIHSYTATQKTVDGPSAKDWRGGRTAAQNIIPSSTGAAKAVGKVIPALNGKLTGMSMRVPTSNVSVVDLTCRTEKPVSYDEIKATVKKYAEGELKGIMGYTEDDVVSTDMNGNSNSSVFDAKAGIALNSNFIKLVSWYDNEWGYSRRVVDLIVYISKVDGNA |
Structure Information |
PDB ID | none, but structures of some homologues available |
Quaternary structure | |
SCOP | NA |
CATH | NA |
TM Helix Prediction | no TM helices |
DisProt Annotation | Not in DisProt |
Predicted Disorder Regions | 1-3, 332-337 |
Connections to Disease |
OMIM ID | |
Function 1 |
Function description | GAPDH, in glycolysis, catalyzing the phosphorylation of glyceraldehyde-3-phosphate to D-glycerate 1,3-bisphosphate |
References for function | 18927407 |
E.C. number | |
Location of functional site(s) | |
Cellular location of function | cytoplasm |
Comments | |
Function 2 |
Function description | adhesin |
References for function | 24128375 |
E.C. number | |
Location of functional site(s) | |
Cellular location of function | surface |
Comments | |