General Information |
MoonProt ID | 396 |
First appeared in release | 2.0 |
Name(s) | VHA-B1, V-type proton ATPase subunit B1, Gene: VHA-B1 |
UniProt ID | P11574 (VATB1_ARATH) |
GO terms | GO:0006810 transport
GO:0006811 ion transport
GO:0010255 glucose mediated signaling pathway
GO:0015991 ATP hydrolysis coupled proton transport
GO:0015992 proton transport
GO:0030835 negative regulation of actin filament depolymerization
GO:0046034 ATP metabolic process
GO:0046686 response to cadmium ion
GO:0051017 actin filament bundle assembly
GO:0051693 actin filament capping
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0051015 actin filament binding
GO:0005773 vacuole
GO:0005774 vacuolar membrane
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0009506 plasmodesma
GO:0009507 chloroplast
GO:0016020 membrane
GO:0033180 proton-transporting V-type ATPase, V1 domain
GO:0005829 cytosol |
Organisms for which functions have been demonstrated | Arabidopsis thaliana (Mouse-ear cress, a plant) |
Sequence length | 486 amino acids |
FASTA sequence | >sp|P11574|VATB1_ARATH V-type proton ATPase subunit B1 OS=Arabidopsis thaliana GN=VHA-B1 PE=2 SV=2
MGTNDLDIEEGTLEIGMEYRTVSGVAGPLVILDKVKGPKYQEIVNIRLGDGSTRRGQVLEVDGEKAVVQVFEGTSGIDNKFTTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGISTIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEKTVDLLEDHGEDNFAIVFAAMGVNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGRKGSITQIPILTMPNDDITHPTPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYANYAIGKDVQAMKAVVGEEALSSEDLLYLEFLDKFERKFVMQGAYDTRNIFQSLDLAWTLLRIFPRELLHRIPAKTLDQFYSRDSTS |
Structure Information |
PDB ID | |
Quaternary structure | |
SCOP | |
CATH | |
TM Helix Prediction | no TM helices |
DisProt Annotation | Not in DisProt |
Predicted Disorder Regions | 1-13, 191-195, 382-386, 481-486 |
Connections to Disease |
OMIM ID | |
Function 1 |
Function description | subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase functions in acidifying several intracellular compartments in eukaryotic cells |
References for function | |
E.C. number | |
Location of functional site(s) | |
Cellular location of function | membrane |
Comments | |
Function 2 |
Function description | binds to hexokinase 1 and the 19S regulatory particle of proteasome subunit (RPT5B) to modulate transcription of specific target genes |
References for function | 17081979 |
E.C. number | |
Location of functional site(s) | |
Cellular location of function | nucleus |
Comments | |