| General Information |
| MoonProt ID | 406 |
| First appeared in release | 3.0 |
| Name(s) | peroxisomal catalase, gene: CAT1 |
| UniProt ID | O13289 |
| GO terms | GO:0004096 catalase activity
GO:0005515 protein binding
GO:0009267 cellular response to starvation
GO:0030447 filamentous growth
GO:0020037 heme binding
GO:0042744 hydrogen peroxide catabolic process
GO:0004096 catalase activity
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0042542 response to hydrogen peroxide
GO:0020037 heme binding
GO:0055114 oxidation-reduction process
GO:0004096 catalase activity
GO:0006979 response to oxidative stress
GO:0046872 metal ion binding
GO:0055114 oxidation-reduction process
GO:0004601 peroxidase activity
GO:0042744 hydrogen peroxide catabolic process
GO:0005777 peroxisome
GO:0016491 oxidoreductase activity
GO:0004096 catalase activity
GO:0005777 peroxisome
GO:0098869 cellular oxidant detoxification
GO:0009277 fungal-type cell wall
GO:0051701 interaction with host
GO:0005515 protein binding
|
| Organisms for which functions have been demonstrated | Candida albicans (yeast, a fungi, can cause candiadiasis) |
| Sequence length | 485 amino acids |
| FASTA sequence | >sp|O13289|CATA_CANAL Peroxisomal catalase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=CAT1 PE=2 SV=5
MAPTFTNSNGQPIPEPFATQRVGQHGPLLLQDFNLIDSLAHFDRERIPERVVHAKGSGAYGVFEVTDDITDICAAKFLDTVGKKTRIFTRFSTVGGELGSADTARDPRGFATKFYTEEGNLDLVYNNTPVFFIRDPSKFPHFIHTQKRNPETHLKDANMFWDYLTSNEESIHQVMVLFSDRGTPASYREMNGYSGHTYKWSNKKGEWFYVQVHFISDQGIKTLTNEEAGALAGSNPDYAQEDLFKNIAAGNYPSWTAYIQTMTEAEAKEAEFSVFDLTKVWPHKKYPLRRFGKFTLNENPKNYFAEVEQAAFSPAHTVPYMEPSADPVLQSRLFSYADTHRHRLGTNYTQIPVNCPVTGAVFNPHMRDGAMTVNGNLGSHPNYLASDKPVEFKQFSLQEDQEVWNGAATPFHWKATPADFKQAQELWKVLKRYPNQQEHLAHNIAVHAAGADAAIQDRVFAYFGKVSQDLADAIKKEVLELSPRK |
| Structure Information |
| PDB ID | NA |
| Quaternary structure | Homotetramer |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | Use FASTA sequence on the MFDp2 webserver.
moonID_406_uniID_O13289 is 485 residues long, with 32 residues (6.60%) predicted as disordered.The protein has 2 short (< 30 residues) disorder segments and 0 long (>= 30 residues) disorder segments.
Segment 1 - Short (< 30 residues) disordered segment Segment is located between positions 1 and 19 in the sequence. The segment is 19 residues long (3.92 % of the total sequence length).
Segment 2 - Short (< 30 residues) disordered segment Segment is located between positions 385 and 397 in the sequence. The segment is 13 residues long (2.68 % of the total sequence length). |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | catalase activity |
| References for function | Poltermann, S.; Kunert, A.; Von Der Heide, M.; Eck, R.; Hartmann, A.; Zipfel, P.F. Gpm1p is a factor H-, FHL-1-, and plasminogen-binding surface protein of Candida albicans. J. Biol. Chem. 2007, 282, 37537–37544. |
| E.C. number | 1.11.1.6 |
| Location of functional site(s) | NA |
| Cellular location of function | cytosol |
| Comments | NA |
| Function 2 |
| Function description | HPG-binding |
| References for function | 17959597 |
| E.C. number | NA |
| Location of functional site(s) | NA |
| Cellular location of function | extracellular |
| Comments | NA |