Protein Information

General Information
MoonProt ID4090
First appeared in release4.0
Name(s)Enolase
UniProt IDB3WCW7
GO terms"GO:0000287 magnesium ion binding GO:0004634 phosphopyruvate hydratase activity GO:0016829 lyase activity GO:0046872 metal ion binding GO:0006096 glycolytic process GO:0005576 extracellular region GO:0005737 cytoplasm GO:0009986 cell surface GO:0000015 phosphopyruvate hydratase complex"
Organisms for which functions have been demonstratedLacticaseibacillus casei (strain BL23) (Lactobacillus casei)
Sequence length434.0
FASTA sequence">sp|B3WCW7|ENO_LACCB Enolase OS=Lacticaseibacillus casei (strain BL23) OX=543734 GN=eno PE=3 SV=1 MSIITDVLAREVLDSRGNPTVEVELYTEDGGFGRALVPSGASTGEHEAVELRDGDKDRFG GKGVLKAVGHVNNEIAKAVIGHDVTEQRLIDQTMIDLDGTPNKGKFGANAILGVSLAAAR AAADEVGLPLYQYLGGPNAHVLPTPMMNVLNGGAHSTNTVDFQEFMIMPVGAKSVREAVR MGSETFHALQALLKSKGDITAVGDEGGFAPNLKDNEEAFELLVEAIKKAGYKPGDDIALA FDVAASEMYDAESKTYTTKWSNPDKKYTTEEWTDMIDGYINKYPIVSVEDPIDENDWEGW QTFTKKMGDKVQIVGDDLFVTNTDYLKKGIDMGVANSILIKLNQIGTLTETFEAIEMAKE AGYTAVVSHRSGETEDTTIADLVVATNAGQIKTGSMSRTDRIAKYNQLMRIEDQLGAQSL YKGRKSFYNVKAID"
Structure Information
PDB IDNA
Quaternary structureNA
SCOP
CATH
TM Helix Predictionno TM helices
DisProt Annotation
Predicted Disorder Regions
Connections to Disease
OMIM ID
Function 1
Function descriptionenzyme, enolase, 2-phospho-D-glycerate => phosphoenolpyruvate + H2O Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. Carbohydrate degradation, glycolysis
References for function_
E.C. numberEC:4.2.1.11
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionbinds fibronectin, binds collagen
References for functionMunoz-Provencio D, Monedero V. Shotgun phage display of Lactobacillus casei BL23 against collagen and fibronectin. J Microbiol Biotechnol. 2011 Feb;21(2):197-203. doi: 10.4014/jmb.1009.09011. PMID: 21364304.
E.C. number
Location of functional site(s)
Cellular location of functioncell surface
Comments