| General Information |
| MoonProt ID | 4093 |
| First appeared in release | 4.0 |
| Name(s) | Chaperonin GroEL |
| UniProt ID | B3W9W7 |
| GO terms | "GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016853 isomerase activity
GO:0051082 unfolded protein binding
GO:0140662 ATP-dependent protein folding chaperone
GO:0006457 protein folding
GO:0042026 protein refolding
GO:0005737 cytoplasm" |
| Organisms for which functions have been demonstrated | "
Lacticaseibacillus casei (strain BL23) (Lactobacillus casei)" |
| Sequence length | 544.0 |
| FASTA sequence | ">sp|B3W9W7|CH60_LACCB Chaperonin GroEL OS=Lacticaseibacillus casei (strain BL23) OX=543734 GN=groEL PE=3 SV=1
MAKEIKFSEDARAAMLRGVDQLANTVKTTLGPKGRNVVLDKSYGSPEITNDGVTIAKSID
LEDHYENMGAKLVAEVASKTNDIAGDGTTTATVLAQSIIREGMKNVTAGANPVGIRTGIE
KATKAAVDELHKISHKVNGKKEIAQVASVSSSNTEVGSLIADAMEKVGHDGVITIEESKG
IDTELSVVEGMQFDRGYLSQYMVTDNDKMEADLDDPYILITDKKISNIQDILPLLQEIVQ
QGKALLIIADDVAGEALPTLVLNKIRGTFNVVAVKAPGFGDRRKAQLEDIATLTGGTVIS
SDLGLDLKDTKLEQLGRAGKVTVTKDNTTIVDGAGSKDAIAERVNIIKKQIDDTTSDFDR
EKLQERLAKLAGGVAVVKVGAATETELKERKYRIEDALNATRAAVEEGYVAGGGTALVDV
LPAVAALKEEGDVQTGINIVLRALEEPVRQIAENAGKEGSVIVEQLKKEKQGVGYNAATD
EWEDMAKSGIIDPTKVTRSALQNAASVAALMLTTEAVVADKPDPNANNNAAAGANPAAGM
GGMM" |
| Structure Information |
| PDB ID | NA |
| Quaternary structure | NA |
| SCOP | |
| CATH | |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | |
| Predicted Disorder Regions | |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | molecular chaperone |
| References for function | _ |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | binds fibronectin, binds collagen |
| References for function | Munoz-Provencio D, Monedero V. Shotgun phage display of Lactobacillus casei BL23 against collagen and fibronectin. J Microbiol Biotechnol. 2011 Feb;21(2):197-203. doi: 10.4014/jmb.1009.09011. PMID: 21364304. |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |