| General Information |
| MoonProt ID | 4118 |
| First appeared in release | 4.0 |
| Name(s) | Elongation factor G |
| UniProt ID | A4VSN3 |
| GO terms | "GO:0000166 nucleotide binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0006412 translation
GO:0006414 translational elongation
GO:0032790 ribosome disassembly
GO:0005737 cytoplasm" |
| Organisms for which functions have been demonstrated | Streptococcus suis |
| Sequence length | 693 |
| FASTA sequence | ">sp|A4VSN3|EFG_STRSY Elongation factor G OS=Streptococcus suis (strain 05ZYH33) OX=391295 GN=fusA PE=3 SV=1
MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHERLQANAHPIQLPIGSEDEFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLEQAEEYREKLVEAVAETDEELMMKYLEGEEITNDELKAAIRKATINVEFFPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGVNPDTDAEEERHASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVLNSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYAGDIAAAVGLKDTTTGDSLTDEKAKIILESIHVPEPVIQLMVEPKSKADQDKMGIALSKLAEEDPTFRVETNVETGETVISGMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPIVDVKAKLYDGSYHDVDSSETAFKVAASLALKEAAKSAQPTILEPMMLVTITAPEDNLGDVMGHVTARRGRVDGMEARGNTQIVRAYVPLAEMFGYATVLRSATQGRGTFMMVFDHYEDVPKSVQDEIIKKNGGNA" |
| Structure Information |
| PDB ID | NA |
| Quaternary structure | NA |
| SCOP | |
| CATH | |
| TM Helix Prediction | 0 |
| DisProt Annotation | |
| Predicted Disorder Regions | |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | translation elongation factor G; involved in protein sythesis on the ribosome |
| References for function | _ |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm, associates with ribosome |
| Comments | |
| Function 2 |
| Function description | binds host collagene type I and fibronectin; acts as a mediator of microbial colonization |
| References for function | Zhang, H., Zheng, J., Yi, L. et al. The identification of six novel proteins with fibronectin or collagen type I binding activity from Streptococcus suis serotype 2. J Microbiol. 52, 963–969 (2014). https://doi.org/10.1007/s12275-014-4311-x |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | Cell surface/membrane |
| Comments | |