| General Information |
| MoonProt ID | 429 |
| First appeared in release | 3.0 |
| Name(s) | Transaldolase, TAL1, Gene = CTRG_00726 |
| UniProt ID | C5M3T7 |
| GO terms | GO:0005975 carbohydrate metabolic process
GO:0006098 pentose-phosphate shunt
GO:0003824 catalytic activity
GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
GO:0005737 cytoplasm
GO:0016740 transferase activity |
| Organisms for which functions have been demonstrated | Candida tropicalis (yeast, a fungi) |
| Sequence length | 323 amino acids |
| FASTA sequence | >tr|C5M3T7|C5M3T7_CANTT Transaldolase OS=Candida tropicalis (strain ATCC MYA-3404 / T1) OX=294747 GN=CTRG_00726 PE=3 SV=1
MSSNSLEQLKATGTTIVTDTGEFEQIAKYKPQDATTNPSLILAAAKNPDYASVIDVAIEYAKEKGSTPREKAEVALDRLLIEFGKRILDIVPGRVSTEVDARLSFDKEATIKKALQLIDLYKAQGIDKSRILIKIASTWEGIQAARELESKHGIHCNLTLLFNFAQAVACAEAGVTLISPFVGRILDWYKASTGETYTAETDPGVKSVKEIYTYYKKYGYNTIVMGASFRNTGEIKALAGVDFLTISPKLLEELYNSTDAVPTVLDVETAKASDIEKVTFVDDEAAFRFALNEDAMATEKLSQGIRQFGKDAVTLLTELEKRF |
| Structure Information |
| PDB ID | NA |
| Quaternary structure | NA |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | Use FASTA sequence on the MFDp2 webserver.
moonID_429_uniID_C5M3T7 is 323 residues long, with 15 residues (4.64%) predicted as disordered.The protein has 2 short (< 30 residues) disorder segments and 0 long (>= 30 residues) disorder segments.
Segment 1 - Short (< 30 residues) disordered segment Segment is located between positions 1 and 4 in the sequence. The segment is 4 residues long (1.24 % of the total sequence length).
Segment 2 - Short (< 30 residues) disordered segment Segment is located between positions 266 and 276 in the sequence. The segment is 11 residues long (3.41 % of the total sequence length). |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | transaldolase, Enzyme, second step of pentose-phosphate pathway; D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate |
| References for function | 27474405 |
| E.C. number | 2.2.1.2 |
| Location of functional site(s) | NA |
| Cellular location of function | cytoplasm |
| Comments | NA |
| Function 2 |
| Function description | binding to kininogen, binding to ECM proteins (Fibronectin, Laminin and Vitronectin) |
| References for function | NA |
| E.C. number | NA |
| Location of functional site(s) | NA |
| Cellular location of function | cell wall |
| Comments | NA |