Protein Information

General Information
MoonProt ID432
First appeared in release3.0
Name(s)Superoxide dismutase 3
UniProt IDQ96UT6
GO termsGO:0004784 superoxide dismutase activity GO:0006801 superoxide metabolic process GO:0055114 oxidation-reduction process GO:0046872 metal ion binding GO:0055114 oxidation-reduction process GO:0016491 oxidoreductase activity GO:0019430 removal of superoxide radicals
Organisms for which functions have been demonstratedCandida albicans (yeast, a fungi, can cause candiadiasis)
Sequence length206 amino acids
FASTA sequence>tr|Q96UT6|Q96UT6_CANAX Superoxide dismutase OS=Candida albicans OX=5476 GN=Sod3 PE=1 SV=1 MITENEKISLPKIDWALDALEPYISKEINDLHINKHHVAYVNGYNAAIDALEKAVGKRDLKSVVEIQQNIKFHGGGHTNHSLFWKNLAPVSKGGGKHPDTSSALGKQIVAQYGSVSNLIDITNSKLAGIQGSGWAFIVKNKQNGGALDVVTTANQDTISAPHLVPIIAIDAWEHAYYLQYQNVKLDYFKAIWNVINWAEAESRYSA
Structure Information
PDB ID4GUN
Quaternary structureNA
SCOPNA
CATHNA
TM Helix Predictionno TM helices
DisProt AnnotationNot in DisProt
Predicted Disorder RegionsUse FASTA sequence on the MFDp2 webserver. moonID_432_uniID_Q96UT6 is 206 residues long, with 9 residues (4.37%) predicted as disordered.The protein has 1 short (< 30 residues) disorder segment and 0 long (>= 30 residues) disorder segments. Segment 1 - Short (< 30 residues) disordered segment Segment is located between positions 1 and 9 in the sequence. The segment is 9 residues long (4.37 % of the total sequence length).
Connections to Disease
OMIM ID
Function 1
Function descriptionremoves radicals, 2 H+ + 2 superoxide = H2O2 + O2
References for function26636139
E.C. number1.15.1.1
Location of functional site(s)NA
Cellular location of functionNA
CommentsNA
Function 2
Function descriptionbinds to 3 plasma proteins: high-molecular-mass kininogen (HK), factor XII (FXII) and prekallikrein (PPK)
References for function26636139
E.C. numberNA
Location of functional site(s)NA
Cellular location of functioncell surface
CommentsNA