Protein Information

General Information
MoonProt ID460
First appeared in release3.0
Name(s)Transaldolase
UniProt IDQ8G6C9
GO termsGO:0016740 transferase activity GO:0006098 pentose-phosphate shunt GO:0005737 cytoplasm GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity
Organisms for which functions have been demonstratedBifidobacterium longum (strain NCC 2705) (Gram positive bacterium)
Sequence length367 amino acids
FASTA sequence>tr|Q8G6C9|Q8G6C9_BIFLO Transaldolase OS=Bifidobacterium longum (strain NCC 2705) OX=206672 GN=tal PE=3 SV=1 MTEATQRTSDNGVSIWLDDLSRSRIESGSLQDLIANKNVVGVTTNPSIFQKALSQVGPYDAQLKELGKVDVETAVRELTTTDVRNATDIFREIAEATDFVDGRVSIEVDPRLAHDTENTAKQAVELWEKVNRPNAMIKIPATLEGLPAITATLAKGISVNVTLIFSLERYEQVIDAYIEGIAQAAANGHDLKHIGSVASFFVSRVDTAVDKLLEANGSDEAKALEGKAAVANARLAYELFEKKFAEDPRWADLAAKGAKVQRPLWASTGTKNAAYSDCKYVDELVAKHIVNTMPEKTLNALADHGNGAPSIEGTYEESHAIINKLAELGINLKDVTDKLEADGVAAFIKSWDSVLSDVQSGIDRVNA
Structure Information
PDB IDNA
Quaternary structureNA
SCOP
CATH
TM Helix Predictionno TM helices
DisProt Annotation
Predicted Disorder RegionsUse FASTA sequence on MFDp2 webserver. trQ8G6C9Q8G6C9_BIFLO_Tra is 367 residues long, with 0 residues (0.00 %) predicted as disordered. The protein has 0 short (< 30 residues) disorder segments and 0 long (>= 30 residues) disorder segments.
Connections to Disease
OMIM ID
Function 1
Function descriptionTransferase. Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
References for functionVentura M, Canchaya C, Zhang Z, Fitzgerald GF, van Sinderen D. Molecular characterization of hsp20, encoding a small heat shock protein of Bifidobacterium breve UCC2003. Applied and environmental microbiology. 2007 Jul 15;73(14):4695-703.
E.C. number2.2.1.2
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionBinds mucin
References for functionNishiyama K, Takaki T, Sugiyama M, Fukuda I, Aiso M, Mukai T, Odamaki T, Xiao JZ, Osawa R, Okada N. Extracellular vesicles produced by Bifidobacterium longum export mucin-binding proteins. Appl Environ Microbiol. 2020 Jul 31:AEM.01464-20. doi: 10.1128/AEM.01464-20. Epub ahead of print. PMID: 32737132.
E.C. number
Location of functional site(s)
Cellular location of functionextracellular
Comments