| General Information |
| MoonProt ID | 476 |
| First appeared in release | 3.0 |
| Name(s) | DBP1
Protein-serine/threonine phosphatase. |
| UniProt ID | Q8LK65 (Q8LK65_TOBAC) |
| GO terms | GO:0004721 phosphoprotein phosphatase activity
GO:0046872 metal ion binding
GO:0016787 hydrolase activity
GO:0003677 DNA binding |
| Organisms for which functions have been demonstrated | Nicotiana tabacum (Common tobacco, a plant) |
| Sequence length | 384 amino acids |
| FASTA sequence | >tr|Q8LK65|Q8LK65_TOBAC Protein-serine/threonine phosphatase OS=Nicotiana tabacum OX=4097 GN=DBP1 PE=2 SV=1
MCVQESEEVSEEMENLDISKSDENIKIGSLQVEDELGNTQKENCEKNTSSSFSVIRNSFPMESISEDTTIADRKQILSNKFLPTLRSGEWSDIGGRLDMEDTHICIADLAKNFGQSILGEEEAVSFYGVFDGHGGKGAALFVRDFLPRIIVEDADFPLKLEKVVSKSFLETDAAFAKSCSADSDLSSGTTALTAMIFGRSLLVANAGDCRAVLSRGGLAIEMSKDHRPCCVSERTRVESLGGFVDDGYLNGQLGVTRALGDWHIKGLKEVEKGGPLSAEPELKLLTLTKEDEFLIIGSDGIWDVFRSQNAVDFARRRLQEHNNAKLCCKEVVDEAKKRGAIDNLTVVMVCFHSEPPPTIVFQRSRIRKCISAEGLQNLRSLLDG |
| Structure Information |
| PDB ID | NA |
| Quaternary structure | NA |
| SCOP | |
| CATH | |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | |
| Predicted Disorder Regions | Predicted disorder at N terminus (aa 1-21), middle region (aa 29-45), and C terminus (aa 380-384) |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | transcription factor |
| References for function | Carrasco JL, Ancillo G, Mayda E, Vera P. A novel transcription factor involved in plant defense endowed with protein phosphatase activity. EMBO J. 2003 Jul 1;22(13):3376-84. doi: 10.1093/emboj/cdg323. PMID: 12839999; PMCID: PMC165647. |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | nucleus |
| Comments | Due to this bipartite structure, i.e. the presence of the phosphatase and DNA binding domains, we propose to name this protein as DBP1 forDNA-binding protein phosphatase 1. |
| Function 2 |
| Function description | phosphatase |
| References for function | Carrasco JL, Ancillo G, Mayda E, Vera P. A novel transcription factor involved in plant defense endowed with protein phosphatase activity. EMBO J. 2003 Jul 1;22(13):3376-84. doi: 10.1093/emboj/cdg323. PMID: 12839999; PMCID: PMC165647. |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | |
| Comments | Due to this bipartite structure, i.e. the presence of the phosphatase and DNA binding domains, we propose to name this protein as DBP1 forDNA-binding protein phosphatase 1. |