| General Information |
| MoonProt ID | 49 |
| First appeared in release | 1.0 |
| Name(s) | GAPDH
Glyceraldehyde 3-phosphate dehydrogenase
Gene Name: gapB |
| UniProt ID | F9UM10 (F9UM10_LACPL), Unreviewed |
| GO terms | GO:0006006 glucose metabolic process
GO:0055114 oxidation-reduction process
GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding |
| Organisms for which functions have been demonstrated | Lactobacillus plantarum (Gram positive bacterium) |
| Sequence length | 340 |
| FASTA sequence | >gi|334089837|gb|AEG64641.1| glyceraldehyde-3-phosphate dehydrogenase [Lactobacillus plantarum]
MSVKIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNADVSATDDSIVVNGKNYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAKRVLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNCLAPLAFFENKEFGIKVGTMTTIHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRVGVVDGSLTELVAILDKKVTADEVNAAIKKHTEGNESFGYNDDEIVSSDVIGTTFGSIFDPTQTEVTSDGDNQLVKTVAWYDNEYGFTCQMVRTLLKFATL |
| Structure Information |
| PDB ID | 6IQM |
| Quaternary structure | |
| SCOP | NA |
| CATH | 3.30.360.10 |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | GAPDH, enzyme
Glyceraldehyde 3-phosphate dehydrogenase |
| References for function | |
| E.C. number | 1.2.1.12 |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | binds mucin and Caco-2 cells |
| References for function | Kinoshita H, Uchida H, Kawai Y, Kawasaki T, Wakahara N, Matsuo H,Watanabe M, Kitazawa H, Ohnuma S, Miura K, et al: Cell surface Lactobacillus plantarum LA 318 glyceraldehyde-3-phosphate dehydrogenase (GAPDH) adheres to human colonic mucin.J Appl Microbiol. 2008 Jun;104(6):1667-74. doi: 10.1111/j.1365-2672.2007.03679.x. Epub 2008 Jan 9.
PMID: 18194256 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |