Protein Information

General Information
MoonProt ID513
First appeared in release3.0
Name(s)Malate dehydrogenase 2
UniProt IDP40296
GO terms GO:0030060 L-malate dehydrogenase activity GO:0006099 tricarboxylic acid cycle GO:0005739 mitochondrion GO:0005737 cytoplasm GO:0009060 aerobic respiration GO:0030060 L-malate dehydrogenase activity GO:0005975 carbohydrate metabolic process GO:0006099 tricarboxylic acid cycle GO:0016615 malate dehydrogenase activity GO:0019752 carboxylic acid metabolic process GO:0030060 L-malate dehydrogenase activity GO:0055114 oxidation-reduction process GO:0003824 catalytic activity GO:0006108 malate metabolic process GO:0016491 oxidoreductase activity GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0006099 tricarboxylic acid cycle GO:0055114 oxidation-reduction process GO:0016491 oxidoreductase activity GO:0005739 mitochondrion GO:0030060 L-malate dehydrogenase activity GO:0005759 mitochondrial matrix GO:0005759 mitochondrial matrix GO:0006099 tricarboxylic acid cycle GO:0006094 gluconeogenesis GO:0016020 membrane GO:0030060 L-malate dehydrogenase activity GO:0046554 malate dehydrogenase (NADP+) activity GO:0043621 protein self-association GO:0006108 malate metabolic process GO:0006107 oxaloacetate metabolic process GO:0005759 mitochondrial matrix GO:0005739 mitochondrion GO:0030060 L-malate dehydrogenase activity GO:0016615 malate dehydrogenase activity GO:0006734 NADH metabolic process GO:0006099 tricarboxylic acid cycle GO:0005759 mitochondrial matrix GO:0005739 mitochondrion GO:0030060 L-malate dehydrogenase activity GO:0006108 malate metabolic process GO:0005739 mitochondrion GO:0070062 extracellular exosome GO:0070062 extracellular exosome GO:0030060 L-malate dehydrogenase activity GO:0070062 extracellular exosome GO:0003723 RNA binding GO:0003723 RNA binding GO:0006108 malate metabolic process GO:0005739 mitochondrion GO:0005634 nucleus
Organisms for which functions have been demonstratedHomo sapeins (human)
Sequence length340 amimo acids
FASTA sequence>sp|P40926|MDHM_HUMAN Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3 MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
Structure Information
PDB ID4WLE
Quaternary structuren/a
SCOPn/a
CATHn/a
TM Helix Predictionn/a
DisProt Annotationn/a
Predicted Disorder Regionsn/a
Connections to Disease
OMIM IDn/a
Function 1
Function descriptionmalate dehydrogenase, enzyme
References for functionn/a
E.C. number1.1.1.37
Location of functional site(s)n/a
Cellular location of functionmitochondrial matrix
Commentsn/a
Function 2
Function descriptionmRNA binding
References for functionn/a
E.C. numbern/a
Location of functional site(s)n/a
Cellular location of functionn/a
Commentsn/a