| General Information |
| MoonProt ID | 52 |
| First appeared in release | 1.0 |
| Name(s) | GAPDH
Glyceraldehyde-3-phosphate dehydrogenase
|
| UniProt ID | A0A0F2E7M6 |
| GO terms | GO:0006006 glucose metabolic process
GO:0055114 oxidation-reduction process
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding |
| Organisms for which functions have been demonstrated | Oral streptococci (S. anginosus and S. oralis) (Gram positive bacteria) |
| Sequence length | 149 aa |
| FASTA sequence | >tr|A0A0F2E7M6|A0A0F2E7M6_STROR Glyceraldehyde-3-phosphate dehydrogenase OS=Streptococcus oralis subsp. tigurinus GN=gapA PE=3 SV=1
MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHLLKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWANDGVEIVLEATGFFATKAAAEKHLKGGAKKVVITAPGGSDVKTIVFNTNHDTLDGTETVISGASCTTNCLAPMAKALHDNFGIVEGLMTTIHAYTGDQMILDGPHRKGDLRRARAAAVNIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPAGSVTELVAVLDKNVTVDEVNAAMKAASNESYGYTEDPIVSSDILGMSFGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTSQLVRTLEYFAKIAK
|
| Structure Information |
| PDB ID | closest is Streptococcus at 94% amino acid sequence identity |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | GAPDH, Glyceraldehyde-3-phosphate dehydrogenase, enzyme |
| References for function | |
| E.C. number | 1.2.1.12 |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | plasminogen binding |
| References for function | Kinnby B, Booth NA, Svensater G. Plasminogen binding by oral streptococci from dental plaque and inflammatory lesions. Microbiology. 2008 Mar;154(Pt 3):924-31. doi: 10.1099/mic.0.2007/013235-0. PMID:
18310038 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |