| General Information |
| MoonProt ID | 59 |
| First appeared in release | 1.0 |
| Name(s) | GAPDH
GapC
Glyceraldehyde 3-phosphate dehydrogenase
Gene Name: gap
|
| UniProt ID | Q9ALW2 (Q9ALW2_STRAG), Unreviewed |
| GO terms | GO:0006006 glucose metabolic process
GO:0055114 oxidation-reduction process
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding |
| Organisms for which functions have been demonstrated | Streptococcus agalactiae, Streptococcus - group B, serotype III/deltaepsilon, strain J48 (Gram positive bacterium) |
| Sequence length | 336 |
| FASTA sequence | >gi|21666599|gb|AAM73770.1|AF421899_1 glyceraldehyde-3-phosphate dehydrogenase [Streptococcus agalactiae]
MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKDGGFEVNGSFVKVSAEREPANIDWATDGVDIVLEATGFFASKAAAEQHIHANGAKKVVITAPGGNDVKTVVYNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHGYTGDQMVLDGPHRGGDLRRARAAAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVAVLEKDTSVEEINAAMKAAANDSYGYTEDAIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTAQLVRTLEYFAKIAK |
| Structure Information |
| PDB ID | closest is S. agalactiae at 95% amino acid sequence identity |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1, 333-336 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | Glyceraldehyde 3-phosphate dehydrogenase, enzyme |
| References for function | Seifert KN, McArthur WP, Bleiweis AS, Brady LJ. Characterization of group B streptococcal glyceraldehyde-3-phosphate dehydrogenase: surface localization, enzymatic activity, and protein-protein interactions. Can J Microbiol. 2003 May;49(5):350-6.
PMID: 12897829 |
| E.C. number | 1.2.1.12 |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | plasminogen binding |
| References for function | Seifert KN, McArthur WP, Bleiweis AS, Brady LJ. Characterization of group B streptococcal glyceraldehyde-3-phosphate dehydrogenase: surface localization, enzymatic activity, and protein-protein interactions. Can J Microbiol. 2003 May;49(5):350-6.
PMID: 12897829 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |