General Information |
MoonProt ID | 59 |
First appeared in release | 1.0 |
Name(s) | GAPDH
GapC
Glyceraldehyde 3-phosphate dehydrogenase
Gene Name: gap
|
UniProt ID | Q9ALW2 (Q9ALW2_STRAG), Unreviewed |
GO terms | GO:0006006 glucose metabolic process
GO:0055114 oxidation-reduction process
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding |
Organisms for which functions have been demonstrated | Streptococcus agalactiae, Streptococcus - group B, serotype III/deltaepsilon, strain J48 (Gram positive bacterium) |
Sequence length | 336 |
FASTA sequence | >gi|21666599|gb|AAM73770.1|AF421899_1 glyceraldehyde-3-phosphate dehydrogenase [Streptococcus agalactiae]
MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPNMLAHLLKYDTTQGRFDGTVEVKDGGFEVNGSFVKVSAEREPANIDWATDGVDIVLEATGFFASKAAAEQHIHANGAKKVVITAPGGNDVKTVVYNTNHDILDGTETVISGASCTTNCLAPMAKALQDNFGVKQGLMTTIHGYTGDQMVLDGPHRGGDLRRARAAAANIVPNSTGAAKAIGLVIPELNGKLDGAAQRVPVPTGSVTELVAVLEKDTSVEEINAAMKAAANDSYGYTEDAIVSSDIVGISYGSLFDATQTKVQTVDGNQLVKVVSWYDNEMSYTAQLVRTLEYFAKIAK |
Structure Information |
PDB ID | closest is S. agalactiae at 95% amino acid sequence identity |
Quaternary structure | |
SCOP | NA |
CATH | NA |
TM Helix Prediction | no TM helices |
DisProt Annotation | Not in DisProt |
Predicted Disorder Regions | 1, 333-336 |
Connections to Disease |
OMIM ID | |
Function 1 |
Function description | Glyceraldehyde 3-phosphate dehydrogenase, enzyme |
References for function | Seifert KN, McArthur WP, Bleiweis AS, Brady LJ. Characterization of group B streptococcal glyceraldehyde-3-phosphate dehydrogenase: surface localization, enzymatic activity, and protein-protein interactions. Can J Microbiol. 2003 May;49(5):350-6.
PMID: 12897829 |
E.C. number | 1.2.1.12 |
Location of functional site(s) | |
Cellular location of function | cytoplasm |
Comments | |
Function 2 |
Function description | plasminogen binding |
References for function | Seifert KN, McArthur WP, Bleiweis AS, Brady LJ. Characterization of group B streptococcal glyceraldehyde-3-phosphate dehydrogenase: surface localization, enzymatic activity, and protein-protein interactions. Can J Microbiol. 2003 May;49(5):350-6.
PMID: 12897829 |
E.C. number | N/A |
Location of functional site(s) | |
Cellular location of function | cell surface |
Comments | |