| General Information |
| MoonProt ID | 72 |
| First appeared in release | 1.0 |
| Name(s) | Hsp60 chaperone
60 kDa chaperonin
Cpn60
Gene Name: cpn60 |
| UniProt ID | Q8KP52 (Q8KP52_LISMN), Unreviewed |
| GO terms | GO:0044267 cellular protein metabolic process
GO:0000166 nucleotide binding
GO:0005524 ATP binding |
| Organisms for which functions have been demonstrated | Listeria |
| Sequence length | 549 |
| FASTA sequence | >gi|424714947|ref|YP_007015662.1| 60 kDa chaperonin [Listeria monocytogenes serotype 4b str. LL195]
MIGGKYKMAKDIKFSEDARRAMLRGVDQLANAVKVTLGPKGRNVVLEKKFGSPLITNDGVTIAKEIELEDPFENMGAKLVSEVASKTNDVAGDGTTTATVLAQAMIQEGLKNVTAGANPVGVRRGIEKAVATAIEELKAISKPIESKESIAQVAAISSGDEEVGKLIAEAMERVGNDGVITIEESKGFATELDVVEGMQFDRGYTSPYMVTDSDKMEAVLEKPYILITDKKINNIQEILPVLEQVVQQGRPMLIIAEDVEGEAQATLVLNKLRGTFNVVAVKAPGFGDRRKAMLEDIAILTGGQVITEDLGLELKTATVDQLGTANKVVVTKDDTTIVEGAGDSTQISARVNQIRAQMEETTSEFDREKLQERLAKLAGGVAVVKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVSIYNKVAALEAEGDVETGINIVLRSLEEPVRQIAHNAGLEGSVIVERLKHEAVGVGFNAANGEWVNMIDAGIVDPTKVTRSALQNASSVAALLLTTEAVVADKPDENGPAAVPDMGMGGMGGMM |
| Structure Information |
| PDB ID | closest is Thermus at 65% amino acid sequence identity |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1-4, 183-184 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | Hsp60 chaperone |
| References for function | |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | mitochondrial matrix |
| Comments | |
| Function 2 |
| Function description | adhesin |
| References for function | Wampler JL, Kim KP, Jaradat Z, Bhunia AK. Heat shock protein 60 acts as a receptor for the Listeria adhesion protein in Caco-2 cells. Infect Immun. 2004 Feb;72(2):931-6.
PMID: 14742538 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |