General Information |
MoonProt ID | 82 |
First appeared in release | 1.0 |
Name(s) | Ornithine carbamoyltransferase
OTCase
Gene Name: argF_3
|
UniProt ID | P0C0N1 |
GO terms | GO:0006520 cellular amino acid metabolic process
GO:0006591 ornithine metabolic process
GO:0004585 ornithine carbamoyltransferase activity
GO:0016597 amino acid binding
GO:0016740 transferase activity
GO:0016743 carboxyl- or carbamoyltransferase activity
GO:0005737 cytoplasm |
Organisms for which functions have been demonstrated | Staphylococcus epidermidis (Gram positive bacterium) |
Sequence length | 333 aa |
FASTA sequence | >sp|P0C0N1|OTC_STAES Ornithine carbamoyltransferase OS=Staphylococcus epidermidis (strain ATCC 12228) GN=argF PE=3 SV=1
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGAHVTYLGPTGSQMGKKETAKDTARVLGGMYDGIEYRGFSQRTVETLAQYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKEYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTEELLNRCERIATENGGNILITDDIDKGVKDSDVIYTDVWVSMGEPDEVWQERLKLLKPYQVNQALLEKTGNPNVIFEHCLPSFHNAETKIGQQIYEKYGISEMEVTDDVFESKASVVFQEAENRMHTIKAVMVATLGEF
|
Structure Information |
PDB ID | closest is Vibrio at 65% amino acid sequence identity |
Quaternary structure | |
SCOP | NA |
CATH | NA |
TM Helix Prediction | no TM helices |
DisProt Annotation | Not in DisProt |
Predicted Disorder Regions | 1-4, 332-333 |
Connections to Disease |
OMIM ID | |
Function 1 |
Function description | Ornithine carbamoyltransferase, enzyme
Carbamoyl phosphate + L-ornithine => phosphate + L-citrulline |
References for function | |
E.C. number | 2.1.3.3 |
Location of functional site(s) | |
Cellular location of function | cytoplasm |
Comments | |
Function 2 |
Function description | bind fibronectin |
References for function | Hussain, M., G. Peters, G. S. Chhatwal, and M. Herrmann. 1999. A lithium chloride-extracted, broad-spectrum-adhesive 42-kilodalton protein of Staphylococcus epidermidis is ornithine carbamoyltransferase. Infect Immun. 1999 Dec;67(12):6688-90. PMID: 10569792 |
E.C. number | N/A |
Location of functional site(s) | |
Cellular location of function | cell surface |
Comments | |