Protein Information

General Information
MoonProt ID82
First appeared in release1.0
Name(s)Ornithine carbamoyltransferase OTCase Gene Name: argF_3
UniProt IDP0C0N1
GO termsGO:0006520 cellular amino acid metabolic process GO:0006591 ornithine metabolic process GO:0004585 ornithine carbamoyltransferase activity GO:0016597 amino acid binding GO:0016740 transferase activity GO:0016743 carboxyl- or carbamoyltransferase activity GO:0005737 cytoplasm
Organisms for which functions have been demonstratedStaphylococcus epidermidis (Gram positive bacterium)
Sequence length333 aa
FASTA sequence>sp|P0C0N1|OTC_STAES Ornithine carbamoyltransferase OS=Staphylococcus epidermidis (strain ATCC 12228) GN=argF PE=3 SV=1 MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGAHVTYLGPTGSQMGKKETAKDTARVLGGMYDGIEYRGFSQRTVETLAQYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKEYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTEELLNRCERIATENGGNILITDDIDKGVKDSDVIYTDVWVSMGEPDEVWQERLKLLKPYQVNQALLEKTGNPNVIFEHCLPSFHNAETKIGQQIYEKYGISEMEVTDDVFESKASVVFQEAENRMHTIKAVMVATLGEF
Structure Information
PDB IDclosest is Vibrio at 65% amino acid sequence identity
Quaternary structure
SCOPNA
CATHNA
TM Helix Predictionno TM helices
DisProt AnnotationNot in DisProt
Predicted Disorder Regions1-4, 332-333
Connections to Disease
OMIM ID
Function 1
Function descriptionOrnithine carbamoyltransferase, enzyme Carbamoyl phosphate + L-ornithine => phosphate + L-citrulline
References for function
E.C. number2.1.3.3
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionbind fibronectin
References for functionHussain, M., G. Peters, G. S. Chhatwal, and M. Herrmann. 1999. A lithium chloride-extracted, broad-spectrum-adhesive 42-kilodalton protein of Staphylococcus epidermidis is ornithine carbamoyltransferase. Infect Immun. 1999 Dec;67(12):6688-90. PMID: 10569792
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments