| General Information |
| MoonProt ID | 89 |
| First appeared in release | 1.0 |
| Name(s) | Phosphoglycerate mutase
|
| UniProt ID | P59159 |
| GO terms | GO:0004619 phosphoglycerate mutase activity
GO:0016853 isomerase activity |
| Organisms for which functions have been demonstrated | Bifidobacterium (Bifidobacterium lactis, B. bifidum, and B. longum) |
| Sequence length | 246 aa |
| FASTA sequence | >sp|P59159|GPMA_BIFLO 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase OS=Bifidobacterium longum (strain NCC 2705) GN=gpmA PE=3 SV=1
MTYKLVLLRHGQSAWNKTNQFTGWVDVPLTEQGEAEAKRGGELLKEKNVLPDIVFTSLLRRAINTANIALDAADRLWIPVQRDWRLNERHYGALQGKNKTEIREEYGDEKFMLWRRSYATPPPEIDPNDQYAQNNDPRYAGDPVPEAECLANVVERVKPYFESAIEPELKAGKTVLIAAHGNSLRAIVKMLDNLSEEEIAKVNIPTAIPLLYELDENFKPIKPRGEYLDPEAAAAGAAAVAAQGQK
|
| Structure Information |
| PDB ID | closest is Mycobacterium at 61% amino acid sequence identity |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1, 241-246 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | Phosphoglycerate mutase, enzyme
1,3-bisphosphoglycerate <=> 2,3-bisphosphoglycerate |
| References for function | |
| E.C. number | 5.4.2.1 |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | plasminogen binding |
| References for function | Candela M, et al. 2007. Binding of human plasminogen to Bifidobacterium.J Bacteriol. 2007 Aug;189(16):5929-36. Epub 2007 Jun 8. PMID: 17557824 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |