| General Information |
| MoonProt ID | 96 |
| First appeared in release | 1.0 |
| Name(s) | Superoxide dismutase
Mn-SOD
SOD-A |
| UniProt ID | P53647 |
| GO terms | |
| Organisms for which functions have been demonstrated | Mycobacterium avium (mycobacterium, causes Johne's disease, a systemic infection of the intestines) |
| Sequence length | 207 aa |
| FASTA sequence | >sp|P53647|SODM_MYCPA Superoxide dismutase [Mn] OS=Mycobacterium paratuberculosis (strain ATCC BAA-968 / K-10) GN=sodA PE=1 SV=3
MAEYTLPDLDWDYAALEPHISGQINEIHHTKHHATYVKGVNDALAKLEEARANEDHAAIFLNEKNLAFHLGGHVNHSIWWKNLSPDGGDKPTGELAAAIDDAFGSFDKFRAQFSAAANGLQGSGWAVLGYDTVGSRLLTFQLYDQQANVPLGIIPLLQVDMWEHAFYLQYKNVKADYVKAFWNVVNWADVQKRYAAATSKAQGLIFG
|
| Structure Information |
| PDB ID | closest is Mycobacterium with 83% amino acid sequence identity |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1, 201-207, |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | Superoxide dismutase, enzyme
antioxidant
convert superoxide anion radicals into O2 and H2O2 |
| References for function | |
| E.C. number | 1.15.1.1 |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | adhesin |
| References for function | Reddy VM, Suleman FG. Mycobacterium avium-superoxide dismutase binds to epithelial cell aldolase, glyceraldehyde-3-phosphate dehydrogenase and cyclophilin A. Microb Pathog. 2004 Feb. PMID: 14687559 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |