Protein Information

General Information
MoonProt ID98
First appeared in release1.0
Name(s)Triose phosphate isomerase TIM TPI Triose-phosphate isomerase Gene Name: TPI1
UniProt IDQ96VN5 (TPIS_PARBA), Reviewed
GO termsGO:0006094 gluconeogenesis GO:0006096 glycolysis GO:0006098 pentose-phosphate shunt GO:0008152 metabolic process GO:0003824 catalytic activity GO:0004807 triose-phosphate isomerase activity GO:0016853 isomerase activity
Organisms for which functions have been demonstratedParacoccidioides brasiliensis
Sequence length249
FASTA sequence>gi|40805818|gb|AAP02959.2| triose phosphate isomerase [Paracoccidioides brasiliensis] MPRKFFVGGNFKMNGTAKSITHIITNLNSAKLDPSTEIVIAPPAIYLVLARQLANGQVAVSAQNVFDKPNGAFTGELSVEQLRDEKITWTLAGHSERRVLLREDDEFVARKTKAAINGGLNVILCIGESLEEREAGKTIDVVTRQLDAVAEEVSPAEWNKVVIAYEPIWAIGTGKVATTEQAQEVHASIRKWLNEKISPEAAENTRVIYGGSVTESNCRDLAAQPDVDGFLVGGASLKPAFVDIINARL
Structure Information
PDB IDclosest is 64% amino acid sequence identity
Quaternary structure
SCOPNA
CATHNA
TM Helix Predictionno TM helices
DisProt AnnotationNot in DisProt
Predicted Disorder Regions
Connections to Disease
OMIM ID
Function 1
Function descriptionTriose phosphate isomerase, enzyme D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate Carbohydrate degradation glycolysis Carbohydrate biosynthesis, gluconeogenesis
References for functionPereira LA, B?o SN, Barbosa MS, da Silva, Felipe MS, de Santana, MendesGiannini MJ, de Almeida. Analysis of the Paracoccidioides brasiliensis triosephosphate isomerase suggests the potential for adhesin function. FEMS Yeast Res. 2007 Dec. PMID: 17714474
E.C. number5.3.1.1
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionadhesin
References for functionPereira LA, B?o SN, Barbosa MS, da Silva, Felipe MS, de Santana, MendesGiannini MJ, de Almeida. Analysis of the Paracoccidioides brasiliensis triosephosphate isomerase suggests the potential for adhesin function. FEMS Yeast Res. 2007 Dec. PMID: 17714474
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments