| General Information |
| MoonProt ID | 98 |
| First appeared in release | 1.0 |
| Name(s) | Triose phosphate isomerase
TIM
TPI
Triose-phosphate isomerase
Gene Name: TPI1
|
| UniProt ID | Q96VN5 (TPIS_PARBA), Reviewed |
| GO terms | GO:0006094 gluconeogenesis
GO:0006096 glycolysis
GO:0006098 pentose-phosphate shunt
GO:0008152 metabolic process
GO:0003824 catalytic activity
GO:0004807 triose-phosphate isomerase activity
GO:0016853 isomerase activity |
| Organisms for which functions have been demonstrated | Paracoccidioides brasiliensis |
| Sequence length | 249 |
| FASTA sequence | >gi|40805818|gb|AAP02959.2| triose phosphate isomerase [Paracoccidioides brasiliensis]
MPRKFFVGGNFKMNGTAKSITHIITNLNSAKLDPSTEIVIAPPAIYLVLARQLANGQVAVSAQNVFDKPNGAFTGELSVEQLRDEKITWTLAGHSERRVLLREDDEFVARKTKAAINGGLNVILCIGESLEEREAGKTIDVVTRQLDAVAEEVSPAEWNKVVIAYEPIWAIGTGKVATTEQAQEVHASIRKWLNEKISPEAAENTRVIYGGSVTESNCRDLAAQPDVDGFLVGGASLKPAFVDIINARL
|
| Structure Information |
| PDB ID | closest is 64% amino acid sequence identity |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | Triose phosphate isomerase, enzyme
D-glyceraldehyde 3-phosphate <=> dihydroxyacetone phosphate
Carbohydrate degradation glycolysis
Carbohydrate biosynthesis, gluconeogenesis
|
| References for function | Pereira LA, B?o SN, Barbosa MS, da Silva, Felipe MS, de Santana, MendesGiannini MJ, de Almeida. Analysis of the Paracoccidioides brasiliensis triosephosphate isomerase suggests the potential for adhesin function. FEMS Yeast Res. 2007 Dec. PMID: 17714474 |
| E.C. number | 5.3.1.1 |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | adhesin |
| References for function | Pereira LA, B?o SN, Barbosa MS, da Silva, Felipe MS, de Santana, MendesGiannini MJ, de Almeida. Analysis of the Paracoccidioides brasiliensis triosephosphate isomerase suggests the potential for adhesin function. FEMS Yeast Res. 2007 Dec. PMID: 17714474 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |