| General Information |
| MoonProt ID | 179 |
| First appeared in release | 1.0 |
| Name(s) | 40S ribosomal protein S14-A
Alternative name(s):
RP59A
CRY1
RPL59
Gene Name: RPS14A
|
| UniProt ID | P06367 (RS14A_YEAST), Reviewed |
| GO terms | GO:0000028 ribosomal small subunit assembly
GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0002181 cytoplasmic translation
GO:0006364 rRNA processing
GO:0006412 translation
GO:0042254 ribosome biogenesis
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0030529 ribonucleoprotein complex
GO:0032040 small-subunit processome |
| Organisms for which functions have been demonstrated | Saccharomyces cerevisiae (yeast, fungi) |
| Sequence length | 137 |
| FASTA sequence | >sp|P06367|RS14A_YEAST 40S ribosomal protein S14-A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPS14A PE=1 SV=5
MSNVVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL
|
| Structure Information |
| PDB ID | 3J6X ,4U51 |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1 to 9, 89-94, 126-137 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | Component of the ribosome small subunit (40S) |
| References for function | |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm, part of the ribosome |
| Comments | |
| Function 2 |
| Function description | represses expression of RPS14B gene
rpS14 binds directly to RNA, binds to an RNA stem-loop structure in RPS14B pre-mRNA |
| References for function | Fewell SW, Woolford JL. Ribosomal protein S14 of Saccharomyces cerevisiae regulates its expression by binding to RPS14B pre-mRNA and to 18S rRNA. Mol Cell Biol. 1999 Jan. PMID: 9858605 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cytosol? or nucleolus? |
| Comments | |