Protein Information

General Information
MoonProt ID179
First appeared in release1.0
Name(s)40S ribosomal protein S14-A Alternative name(s): RP59A CRY1 RPL59 Gene Name: RPS14A
UniProt IDP06367 (RS14A_YEAST), Reviewed
GO termsGO:0000028 ribosomal small subunit assembly GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0002181 cytoplasmic translation GO:0006364 rRNA processing GO:0006412 translation GO:0042254 ribosome biogenesis GO:0003729 mRNA binding GO:0003735 structural constituent of ribosome GO:0005634 nucleus GO:0005730 nucleolus GO:0005737 cytoplasm GO:0005840 ribosome GO:0022627 cytosolic small ribosomal subunit GO:0030529 ribonucleoprotein complex GO:0032040 small-subunit processome
Organisms for which functions have been demonstratedSaccharomyces cerevisiae (yeast, fungi)
Sequence length137
FASTA sequence>sp|P06367|RS14A_YEAST 40S ribosomal protein S14-A OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RPS14A PE=1 SV=5 MSNVVQARDNSQVFGVARIYASFNDTFVHVTDLSGKETIARVTGGMKVKADRDESSPYAAMLAAQDVAAKCKEVGITAVHVKIRATGGTRTKTPGPGGQAALRALARSGLRIGRIEDVTPVPSDSTRKKGGRRGRRL
Structure Information
PDB ID3J6X ,4U51
Quaternary structure
SCOPNA
CATHNA
TM Helix Predictionno TM helices
DisProt AnnotationNot in DisProt
Predicted Disorder Regions1 to 9, 89-94, 126-137
Connections to Disease
OMIM ID
Function 1
Function descriptionComponent of the ribosome small subunit (40S)
References for function
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytoplasm, part of the ribosome
Comments
Function 2
Function descriptionrepresses expression of RPS14B gene rpS14 binds directly to RNA, binds to an RNA stem-loop structure in RPS14B pre-mRNA
References for functionFewell SW, Woolford JL. Ribosomal protein S14 of Saccharomyces cerevisiae regulates its expression by binding to RPS14B pre-mRNA and to 18S rRNA. Mol Cell Biol. 1999 Jan. PMID: 9858605
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncytosol? or nucleolus?
Comments