| General Information |
| MoonProt ID | 202 |
| First appeared in release | 1.0 |
| Name(s) | O-GlcNAc transferase
glycosyl transferase
Gene Name:gmaR |
| UniProt ID | A0A0E0UUG2 |
| GO terms | GO:0008152 metabolic process
GO:0016740 transferase activity |
| Organisms for which functions have been demonstrated | Listeria monocytogenes (Gram positive bacterium, causes listeriosis, septicemia, meningitis) |
| Sequence length | 637 aa |
| FASTA sequence | >tr|F8BDH3|F8BDH3_LISMM Putative glycosyl transferases flagella synthesis antirepressor OS=Listeria monocytogenes serotype 4a (strain M7) GN=gmaR PE=4 SV=1
MRPLISICMIVKNEAHILRQSLASFRKFTEEIIIVDTGSTDETKEIAQEFTDFVYDFEWTGNFSDARNFAAKHATGKWILAIDADECLEEESYRKLEKQLKSPIEPIQMAQIISFTGEKGRVTTTNQMARVYKNDGTICFRGVIHEQLEAVDKHPIAAGVAEVKIYHYGYMTEIVEKQDKSDRNLRLLEKEVKNNKNSGFVHFNIGQEMNRLGNKKEALKEFSEAFRLRDHNHYIWAKLSAYHIAELLEQEKRYDESLAIIEEARIIWPNVPEFPLKKANILYVNHQLEDAKEIYQSLLENTAIDYQPIVLYEATNFMPHKMLGTIYLEEKDYTRAMTHFSKAYAENSSDYGVMFQMIMLLSKFHQPKEIFAFMERHHFISSTETGLRLLSMTTQQGYAELSELIVQSLTDVYPPVAEATEVKIATIRNVFPVISESAILFGIKEELIDAADLCLWHYENPQLPIERVMKNSDVGDIYDFIFENGPRISKKRYLFVLERAIALGKGEFADYLLALRNVYHDSINSHIADLFFQYDFADIALDFYNIVDADEVTKQGYINLINYLVDAEVLDEALAIAERGIDNFSTDFRFYLWTIKIDTENRANRISEAMDEFPNNRYLAKLLDEVTMLQDTVTNNR
|
| Structure Information |
| PDB ID | None |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1, 630-637 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | O-GlcNAc transferase
glycosyltransferase that mediates beta-O-linked GlcNAc modification of flagellin (FlaA) |
| References for function | Shen A, Kamp HD, Gr?ndling A, Higgins DE. A bifunctional O-GlcNAc transferase governs flagellar motility through anti-repression. Genes Dev. 2006 Dec 1. PMID: 17158746 |
| E.C. number | 2.4.1.255 |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | transcriptional regulator
anti-repressor, target is MogR (a transcriptional repressor), binds to MogR and prevents it from binding to DNA |
| References for function | Shen A, Kamp HD, Gr?ndling A, Higgins DE. A bifunctional O-GlcNAc transferase governs flagellar motility through anti-repression. Genes Dev. 2006 Dec 1. PMID: 17158746 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |