| General Information |
| MoonProt ID | 268 |
| First appeared in release | 1.0 |
| Name(s) | Aspartate receptor
Methyl-accepting chemotaxis protein II
MCP-II
Aspartate chemoreceptor protein
Gene Name: tar |
| UniProt ID | P07017 (MCP2_ECOLI), Reviewed |
| GO terms | GO:0006935 chemotaxis
GO:0007165 signal transduction
GO:0004871 signal transducer activity
GO:0004888 transmembrane signaling receptor activity
GO:0005515 protein binding
GO:0043424 protein histidine kinase binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane |
| Organisms for which functions have been demonstrated | Escherichia coli (Gram negative bacterium) |
| Sequence length | 553 |
| FASTA sequence | >sp|P07017|MCP2_ECOLI Methyl-accepting chemotaxis protein II OS=Escherichia coli (strain K12) GN=tar PE=1 SV=2
MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSNQLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAATHYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNAMGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLTPLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASDTAQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRLAASPLTNKPQTPSRPASEQPPAQPRLRIAEQDPNWETF
|
| Structure Information |
| PDB ID | 2ASR 2ASR ligand binding domain only |
| Quaternary structure | |
| SCOP | NA |
| CATH | 1.20.120.30 |
| TM Helix Prediction | 2(7-29, 190-212) |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1-2, 78-86, 113-115, 180-183, 281-304, 517-553 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | aspartate receptor
binds aspartate
transmembrane receptor for aspartate |
| References for function | Wolff C, Parkinson JS. Aspartate taxis mutants of the Escherichia coli tar chemoreceptor. J Bacteriol. 1988 Oct. PMID: 3049535 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | inner membrane, transmembrane protein |
| Comments | |
| Function 2 |
| Function description | binds maltose binding protein
maltose receptor
transmembrane receptor for maltose binding protein
|
| References for function | Wolff C, Parkinson JS. Aspartate taxis mutants of the Escherichia coli tar chemoreceptor. J Bacteriol. 1988 Oct. PMID: 3049535 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | inner membrane, transmembrane protein |
| Comments | |