| General Information |
| MoonProt ID | 299 |
| First appeared in release | 4.0 |
| Name(s) | Hsp70 |
| UniProt ID | I1SV54 |
| GO terms | GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity |
| Organisms for which functions have been demonstrated | Trichomonas vaginalis |
| Sequence length | 659 |
| FASTA sequence | >tr|I1SV54|I1SV54_TRIVA Heat shock protein 70 OS=Trichomonas vaginalis OX=5722 GN=hsp70 PE=3 SV=1
MSAIGIDLGTTYSCVGVFRHNRVDILANDMGNRTTPSYVAFTEDERLVGDAAKNQAAMNP
QNTVFDAKRMIGRKFSDPVVQKDMKHWPFKVVRGDGDRPKIEVQFKGETKQFFPEEISAM
VLGKMKETAENMLSEKITDAVVTVPAYFNDGQRQATKDAGVIAGLNVLRIINEPTAAAIT
FGLNEKSDKERHVLIFDLGGGTFDVSLLDIDGGMFEARATAGDTHLGGEDFDSRLVDYFA
DRFQKKFKCDLRESPRALRTLRTACERAKRTISTAANASILCESLYQGHDFQDTISRAMF
ENLNDELFRSTLGPVAQVLKDAKMSKSDVTDIVLVGGSSRIPRVQQLLQEFFNGKQPCRG
VDPDEAVAYGAAVQAAIIKGDNSEAVKDILLLDVAPLSLGIETAGEIMTVLIPRNTTIPA
KKSNIFTTFADNQPAVTIKVYEGERTRTRDNNLLGTFDLTGIPPAPRGVPQIEVTFDVNA
DGIMNVSAQDKSTGNVKKITIKNDKGRLSQADIDRMVSDAEKYKAQDEEAKKKIEAKNGL
EGYCFGVRNSVNGELGSKIDAADKDAILKVVNDTLAWIDSNQDASTADYEAKQKDVEGQL
MPLMQKAYQSAAGGAGGMPGGVDPSMFQNMGGAGGAAPGAGPSAGARPSGSGPRVEEVD |
| Structure Information |
| PDB ID | NA |
| Quaternary structure | NA |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | NA |
| DisProt Annotation | |
| Predicted Disorder Regions | NA |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | protein chaperone |
| References for function | Figueroa-Angulo EE, Calla-Choque JS, Mancilla-Olea MI, Arroyo R. RNA-Binding Proteins in Trichomonas vaginalis: Atypical Multifunctional Proteins. Biomolecules. 2015 Nov 26;5(4):3354-95. doi: 10.3390/biom5043354. PMID: 26703754; PMCID: PMC4693282. |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | binds RNA and regulates translation |
| References for function | Figueroa-Angulo EE, Calla-Choque JS, Mancilla-Olea MI, Arroyo R. RNA-Binding Proteins in Trichomonas vaginalis: Atypical Multifunctional Proteins. Biomolecules. 2015 Nov 26;5(4):3354-95. doi: 10.3390/biom5043354. PMID: 26703754; PMCID: PMC4693282. |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |