Protein Information

General Information
MoonProt ID323
First appeared in release2.0
Name(s)Ef-Tu, translation elongation factor Tu, Gene: tuf
UniProt IDA8AWA0 (EFTU_STRGC)
GO termsGO:0006412 translation GO:0006414 translational elongation GO:0000166 nucleotide binding GO:0003746 translation elongation factor activity GO:0003924 GTPase activity GO:0005525 GTP binding GO:0005622 intracellular GO:0005737 cytoplasm
Organisms for which functions have been demonstratedStreptococcus gordonii (Gram positive bacterium)
Sequence length398 amino acids
FASTA sequence>sp|A8AWA0|EFTU_STRGC Elongation factor Tu OS=Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288) GN=tuf PE=3 SV=1 MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMDLMNTVDEYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEEIQKAVVTGVEMFRKQLDEGLAGDNVGVLLRGIQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTIEVELIHPIAVEQGTTFSIREGGRTVGSGMVTEIEA
Structure Information
PDB IDnone, closest homologue has 70% amino acid sequence identity
Quaternary structure
SCOPNA
CATHNA
TM Helix Predictionno TM helices
DisProt AnnotationNot in DisProt
Predicted Disorder Regions1-8, 392-398
Connections to Disease
OMIM ID
Function 1
Function descriptiontranslation elongation factor Tu
References for function
E.C. number
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionMucin (MUC7)-binding protein
References for functionKesimer M, Kilic¸ N, Mehrotra R, Thornton DJ, Sheehan JK. (2009) Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii. BMC Microbiol. 9, 163. PMID: 19671172
E.C. number
Location of functional site(s)
Cellular location of functioncell surface
Comments