| General Information |
| MoonProt ID | 323 |
| First appeared in release | 2.0 |
| Name(s) | Ef-Tu, translation elongation factor Tu, Gene: tuf |
| UniProt ID | A8AWA0 (EFTU_STRGC) |
| GO terms | GO:0006412 translation
GO:0006414 translational elongation
GO:0000166 nucleotide binding
GO:0003746 translation elongation factor activity
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0005622 intracellular
GO:0005737 cytoplasm |
| Organisms for which functions have been demonstrated | Streptococcus gordonii (Gram positive bacterium) |
| Sequence length | 398 amino acids |
| FASTA sequence | >sp|A8AWA0|EFTU_STRGC Elongation factor Tu OS=Streptococcus gordonii (strain Challis / ATCC 35105 / CH1 / DL1 / V288) GN=tuf PE=3 SV=1
MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSVNQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDLLSEYDFPGDDLPVIQGSALKALEGDSKYEDIIMDLMNTVDEYIPEPERDTDKPLLLPVEDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEEIQKAVVTGVEMFRKQLDEGLAGDNVGVLLRGIQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQFYFRTTDVTGSIELPAGTEMVMPGDNVTIEVELIHPIAVEQGTTFSIREGGRTVGSGMVTEIEA |
| Structure Information |
| PDB ID | none, closest homologue has 70% amino acid sequence identity |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1-8, 392-398 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | translation elongation factor Tu |
| References for function | |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | Mucin (MUC7)-binding protein |
| References for function | Kesimer M, Kilic¸ N, Mehrotra R, Thornton DJ, Sheehan JK. (2009) Identification of salivary mucin MUC7 binding proteins from Streptococcus gordonii. BMC Microbiol. 9, 163. PMID: 19671172 |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |