| General Information |
| MoonProt ID | 332 |
| First appeared in release | 2.0 |
| Name(s) | enolase, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase Gene: eno |
| UniProt ID | I7WI49 (I7WI49_STRCB) |
| GO terms | GO:0006096 glycolytic process
GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
GO:0000015 phosphopyruvate hydratase complex
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0009986 cell surface |
| Organisms for which functions have been demonstrated | Streptococcus canis, group G Streptococci (Gram positive bacterium) |
| Sequence length | 435 amino acids |
| FASTA sequence | >tr|I7WI49|I7WI49_STRCB Enolase OS=Streptococcus canis FSL Z3-227 GN=eno PE=3 SV=1
MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTGEHEAVELRDGDKSRYLGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPNKGKLGANAILGVSIAVARAAADYLEVPLYTYLGGFNTKVLPTPMMNIINGGSHSDAPIAFQEFMIMPVGAPTFKEGLRWGAEVFHALKKILKERGLVTAVGDEGGFAPKFEGTEDGVETILKAIEAAGYEAGENGIMIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQIDYLEELVNKYPIITIEDGMDENDWDGWKALTERLGGRVQLVGDDFFVTNTEYLARGIKENAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQIKTGSLSRTDRIAKYNQLLRIEDQLGEVAQYKGIKSFYNLKK |
| Structure Information |
| PDB ID | several from Group A streptococcus |
| Quaternary structure | |
| SCOP | |
| CATH | |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1-3, 42, 265-267, 433-435 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | enolase, in glycolysis, 2-phospho-D-glycerate hydro-lyase, 2-phosphoglycerate dehydratase |
| References for function | |
| E.C. number | 4.2.1.11 |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | plasminogen binding |
| References for function | 23481605 |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | |
| Comments | binds to first 4 kringle domains of plasminogen, secretion of enolase and reassociation to surface |