| General Information |
| MoonProt ID | 342 |
| First appeared in release | 4.0 |
| Name(s) | enolase |
| UniProt ID | NA |
| GO terms | NA |
| Organisms for which functions have been demonstrated | Schistoma mansoni, a blood fluke parasite that causes schistomiassis. Affects more than 200 million people worldwide and causes up to 280,000 deaths per year. |
| Sequence length | NA |
| FASTA sequence | NA |
| Structure Information |
| PDB ID | NA |
| Quaternary structure | NA |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | NA |
| DisProt Annotation | NA |
| Predicted Disorder Regions | NA |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | enzyme, enolase, 2-phospho-D-glycerate => phosphoenolpyruvate + H2O Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. Carbohydrate degradation, glycolysis |
| References for function | Figueiredo, B. C., Da'dara, A. A., Oliveira, S. C., & Skelly, P. J. (2015). Schistosomes Enhance Plasminogen Activation: The Role of Tegumental Enolase. PLoS pathogens, 11(12), e1005335. https://doi.org/10.1371/journal.ppat.1005335 |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | |
| Comments | |
| Function 2 |
| Function description | bind plasminogen and stimulate plasmin generation by tissue plasminogen activator |
| References for function | Figueiredo, B. C., Da'dara, A. A., Oliveira, S. C., & Skelly, P. J. (2015). Schistosomes Enhance Plasminogen Activation: The Role of Tegumental Enolase. PLoS pathogens, 11(12), e1005335. https://doi.org/10.1371/journal.ppat.1005335 |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |