| General Information |
| MoonProt ID | 346 |
| First appeared in release | 2.0 |
| Name(s) | GAPDH, glyceraldehyde 3-phosphage dehydrogenase, glyceraldehyde-3-phosphgae dehydrogenase, Gene: gapdh |
| UniProt ID | A8C5S7 (A8C5S7_TALMA) |
| GO terms | GO:0006006 glucose metabolic process
GO:0006096 glycolytic process
GO:0055114 oxidation-reduction process
GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GO:0016491 oxidoreductase activity
GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0050661 NADP binding
GO:0051287 NAD binding |
| Organisms for which functions have been demonstrated | Talaromyces marneffei (Penicillium marneffei) |
| Sequence length | 337 amino acids |
| FASTA sequence | >tr|A8C5S7|A8C5S7_TALMA Glyceraldehyde-3-phosphate dehydrogenase OS=Talaromyces marneffei GN=gapdh PE=2 SV=1
MVTKVGINGFGRIGRIVFRNVIEHDDAEVVAVNDPFIETHYAAYMLKYDTQHGQFKGTIEVEGSDLIVNGKRVKFYQERDPANIKWSETGAAYIVESTGVFTTTEKASAHLKGGAKKVVISAPSADAPMFVMGVNHTTYKSSDTIISNASCTTNCLAPLAKIVNDNWGLVEGLMTTIHSYTATQKTVDGPSAKDWRGGRTAAQNIIPSSTGAAKAVGKVIPALNGKLTGMSMRVPTSNVSVVDLTCRTEKPVSYDEIKATVKKYAEGELKGIMGYTEDDVVSTDMNGNSNSSVFDAKAGIALNSNFIKLVSWYDNEWGYSRRVVDLIVYISKVDGNA |
| Structure Information |
| PDB ID | none, but structures of some homologues available |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1-3, 332-337 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | GAPDH, in glycolysis, catalyzing the phosphorylation of glyceraldehyde-3-phosphate to D-glycerate 1,3-bisphosphate |
| References for function | 18927407 |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | adhesin |
| References for function | 24128375 |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | surface |
| Comments | |