| General Information |
| MoonProt ID | 368 |
| First appeared in release | 2.0 |
| Name(s) | outer dense fiber protein 2, Gene: ODF2 |
| UniProt ID | Q5BJF6 (ODFP2_HUMAN) |
| GO terms | GO:0000086 G2/M transition of mitotic cell cycle
GO:0007275 multicellular organism development
GO:0007283 spermatogenesis
GO:0007286 spermatid development
GO:0030154 cell differentiation
GO:1902017 regulation of cilium assembly
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0017137 Rab GTPase binding
GO:0000922 spindle pole
GO:0001520 outer dense fiber
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005815 microtubule organizing center
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0005929 cilium
GO:0036064 ciliary basal body
GO:0042995 cell projection
GO:0072372 primary cilium
GO:0097539 ciliary transition fiber |
| Organisms for which functions have been demonstrated | Homo sapiens (human, a mammal) |
| Sequence length | 829 amino acids |
| FASTA sequence | >sp|Q5BJF6|ODFP2_HUMAN Outer dense fiber protein 2 OS=Homo sapiens GN=ODF2 PE=1 SV=1
MSASSSGGSPRFPSCGKNGVTSLTQKKVLRAPCGAPSVTVTKSHKRGMKGDTVNVRRSVRVKTKVPWMPPGKSSARPVGCKWENPPHCLEITPPSSEKLVSVMRLSDLSTEDDDSGHCKMNRYDKKIDSLMNAVGCLKSEVKMQKGERQMAKRFLEERKEELEEVAHELAETEHENTVLRHNIERMKEEKDFTILQKKHLQQEKECLMSKLVEAEMDGAAAAKQVMALKDTIGKLKTEKQMTCTDINTLTRQKELLLQKLSTFEETNRTLRDLLREQHCKEDSERLMEQQGALLKRLAEADSEKARLLLLLQDKDKEVEELLQEIQCEKAQAKTASELSKSMESMRGHLQAQLRSKEAENSRLCMQIKNLERSGNQHKAEVEAIMEQLKELKQKGDRDKESLKKAIRAQKERAEKSEEYAEQLHVQLADKDLYVAEALSTLESWRSRYNQVVKEKGDLELEIIVLNDRVTDLVNQQQTLEEKMREDRDSLVERLHRQTAEYSAFKLENERLKASFAPMEDKLNQAHLEVQQLKASVKNYEGMIDNYKSQVMKTRLEADEVAAQLERCDKENKILKDEMNKEIEAARRQFQSQLADLQQLPDILKITEAKLAECQDQLQGYERKNIDLTAIISDLRSRIEHQGDKLEMAREKHQASQKENKQLSLKVDELERKLEATSAQNIEFLQVIAKREEAIHQSQLRLEEKTRECGTLARQLESAIEDARRQVEQTKEHALSKERAAQNKILDLETQLSRTKTELSQLRRSRDDADRRYQSRLQDLKDRLEQSESTNRSMQNYVQFLKSSYANVFGDGPYSTFLTSSPIRSRSPPA |
| Structure Information |
| PDB ID | |
| Quaternary structure | |
| SCOP | |
| CATH | |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1-59, 68-120, 145-202, 239-243, 277-294, 299-323, 325-347, 355-360, 377, 385-421, 476-507, 559-561, 566-580, 585-591, 640-659, 675-708, 719-741, 748-770, 783-791, 813-829 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | component of sperm tail outer dense fibers |
| References for function | |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | sperm tail |
| Comments | |
| Function 2 |
| Function description | interactions with zona pellucida proteins of egg |
| References for function | 23355646 |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | head of sperm, sperm membrane |
| Comments | |