| General Information |
| MoonProt ID | 378 |
| First appeared in release | 2.0 |
| Name(s) | pinin, Gene: PNN |
| UniProt ID | Q9H307 (PININ_HUMAN) |
| GO terms | GO:0000398 mRNA splicing, via spliceosome
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006397 mRNA processing
GO:0007155 cell adhesion
GO:0008380 RNA splicing
GO:0003677 DNA binding
GO:0005198 structural molecule activity
GO:0044822 poly(A) RNA binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005681 spliceosomal complex
GO:0005882 intermediate filament
GO:0005886 plasma membrane
GO:0005911 cell-cell junction
GO:0016020 membrane
GO:0016607 nuclear speck
GO:0030054 cell junction
GO:0030057 desmosome
GO:0071013 catalytic step 2 spliceosome
GO:0035145 exon-exon junction complex |
| Organisms for which functions have been demonstrated | Homo sapiens (human, a mammal) |
| Sequence length | 717 amino acids |
| FASTA sequence | >sp|Q9H307|PININ_HUMAN Pinin OS=Homo sapiens GN=PNN PE=1 SV=4
MAVAVRTLQEQLEKAKESLKNVDENIRKLTGRDPNDVRPIQARLLALSGPGGGRGRGSLLLRRGFSDSGGGPPAKQRDLEGAVSRLGGERRTRRESRQESDPEDDDVKKPALQSSVVATSKERTRRDLIQDQNMDEKGKQRNRRIFGLLMGTLQKFKQESTVATERQKRRQEIEQKLEVQAEEERKQVENERRELFEERRAKQTELRLLEQKVELAQLQEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQINKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEEEKEIAIVHSDAEKEQEEEEQKQEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSENEASKELEPEMEFEIEPDKECKSLSPGKENVSALDMEKESEEKEEKESEPQPEPVAQPQPQSQPQLQLQSQSQPVLQSQPPSQPEDLSLAVLQPTPQVTQEQGHLLPERKDFPVESVKLTEVPVEPVLTVHPESKSKTKTRSRSRGRARNKTSKSRSRSSSSSSSSSSSTSSSSGSSSSSGSSSSRSSSSSSSSTSGSSSRDSSSSTSSSSESRSRSRGRGHNRDRKHRRSVDRKRRDTSGLERSHKSSKGGSSRDTKGSKDKNSRSDRKRSISESSRSGKRSSRSERDRKSDRKDKRR |
| Structure Information |
| PDB ID | |
| Quaternary structure | |
| SCOP | |
| CATH | |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1-11, 34-113, 116-139, 158-194, 277-390, 401-529, 551-717 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | transcriptional activator |
| References for function | 15542832 |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | nucleus |
| Comments | |
| Function 2 |
| Function description | binds RNA, involved in splicing of pre-mRNAs |
| References for function | 12051732 |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | |
| Comments | |