Protein Information

General Information
MoonProt ID385
First appeared in release2.0
Name(s)Leucyl aminopeptidase Gene: pepA
UniProt IDQ4A9M4
GO termsGO:0006508 proteolysis GO:0019538 protein metabolic process GO:0004177 aminopeptidase activity GO:0008233 peptidase activity GO:0008235 metalloexopeptidase activity GO:0016787 hydrolase activity GO:0030145 manganese ion binding GO:0046872 metal ion binding GO:0005622 intracellular GO:0005737 cytoplasm
Organisms for which functions have been demonstratedMycoplasma hyopneumoniae
Sequence length459 amino acids
FASTA sequence>tr|Q4A9M4|Q4A9M4_MYCHJ Leucyl aminopeptidase OS=Mycoplasma hyopneumoniae (strain J / ATCC 25934 / NCTC 10110) GN=pepA PE=4 SV=2 MKNFSEIFIKYSNKFESNRITIEPAYSDSQIPMLIKEDLAITEYLGQKKAYINLGSRSKELTPNRFRKIAAKLGHYPRDMQINFDKFPNSFLRYLIEVIAFQRSDIFSLRADYAKNRAKNRDILVVSSYLDELKPIIDKYQIINNSVNYARYYQNMPPNMASSEFLASEIQKKMNLNPKLTVKVLGENEVRKLGMNLLLAVNRGSTYDAKLVVISYEGLPGSQYKTAFIGKGITFDSGGYNIKTGMYMNDMKIDMSGAIICAAAIDALSQFNPLANVVAVLPLTDNRLNGDANTPDAVWRSMNGKTVEINNTDAEGRLILADAITYAIRQEKASEIISIATLTGAIRIALGETFTGAFANEEKIWKNFNEASKEAGELIWRMPLHQDFAQNIRDSKVADLKNTDFSGKAGSSSAAMFLAEFVEDKPFIHLDIAATAFVKNTPTGVMVRSLVEYILAKQN
Structure Information
PDB ID
Quaternary structure
SCOP
CATH
TM Helix Predictionno TM helices
DisProt AnnotationNot in DisProt
Predicted Disorder Regions1-9, 110-117, 457-459
Connections to Disease
OMIM ID
Function 1
Function description leucine aminopeptidase (LAP)
References for function 25589579
E.C. numberEC:3.4.11.1
Location of functional site(s)
Cellular location of functionCell surface of Mycoplasma hyopneumoniae (pg 4)
Comments
Function 2
Function descriptionbinds to heparin
References for functionJarocki VM, Santos J, Tacchi JL, Raymond BB, Deutscher AT, Jenkins C, Padula MP, Djordjevic SP. MHJ_0461 is a multifunctional leucine aminopeptidase on the surface of Mycoplasma hyopneumoniae. Open Biol. 2015 Jan;5(1):140175. doi: 10.1098/rsob.140175. PMID: 25589579.
E.C. number
Location of functional site(s)
Cellular location of functionCell surface of Mycoplasma hyopneumoniae
Comments