General Information |
MoonProt ID | 388 |
First appeared in release | 2.0 |
Name(s) | RPT5B, 26S protease regulatory subunit 6A homolog B, 26S proteasome AAA-ATPase subunit RPT5b, Proteasome 26S subunit 6A homolog B, Regulatory particle triple-A ATPase subunit 5b, Tat-binding protein 1 homolog B, TBP-1 homolog B, Gene: RPT5B |
UniProt ID | O04019 (PS6AB_ARATH) |
GO terms | GO:0009553 embryo sac development
GO:0009555 pollen development
GO:0010255 glucose mediated signaling pathway
GO:0010498 proteasomal protein catabolic process
GO:0030163 protein catabolic process
GO:0030433 ER-associated ubiquitin-dependent protein catabolic process
GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly
GO:1901800 positive regulation of proteasomal protein catabolic process
GO:0000166 nucleotide binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0017025 TBP-class protein binding
GO:0036402 proteasome-activating ATPase activity
GO:0000502 proteasome complex
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0008540 proteasome regulatory particle, base subcomplex
GO:0016020 membrane
GO:0031595 nuclear proteasome complex
GO:0031597 cytosolic proteasome complex |
Organisms for which functions have been demonstrated | Arabidopsis thaliana (Mouse-ear cress, a plant) |
Sequence length | 423 amino acids |
FASTA sequence | >sp|O04019|PS6AB_ARATH 26S protease regulatory subunit 6A homolog B OS=Arabidopsis thaliana GN=RPT5B PE=1 SV=3
MATAMAEDTSFEGDQLASMTTDDIGRASRLLANEIRILKEESQRTNLDLESVKEKIKENQEKIKLNKQLPYLVGNIVEILEMSPEDDAEEDGANIDLDSQRKGKCVVLKTSTRQTIFLPVVGLVDPDTLKPGDLVGVNKDSYLILDTLPSEYDSRVKAMEVDEKPTEDYNDIGGLEKQIQELVEAIVLPMTHKEQFEKLGIRPPKGVLLYGPPGTGKTLMARACAAQTNATFLKLAGPQLVQMFIGDGAKLVRDAFLLAKEKSPCIIFIDEIDAIGTKRFDSEVSGDREVQRTMLELLNQLDGFSSDDRIKVIAATNRADILDPALMRSGRLDRKIEFPHPTEEARGRILQIHSRKMNVNADVNFEELARSTDDFNGAQLKAVCVEAGMLALRRDATEVNHEDFNEGIIQVQAKKKASLNYYA |
Structure Information |
PDB ID | |
Quaternary structure | |
SCOP | |
CATH | |
TM Helix Prediction | no TM helices |
DisProt Annotation | Not in DisProt |
Predicted Disorder Regions | 1-15, 88-94, 278-287, 413-423 |
Connections to Disease |
OMIM ID | |
Function 1 |
Function description | part of the regulatory ATPase complex of the 26S proteasome, confers substrate specificity and need for ATP to the proteaseome |
References for function | |
E.C. number | |
Location of functional site(s) | |
Cellular location of function | cytoplasm |
Comments | |
Function 2 |
Function description | binds to hexokinase 1 and VHA B1 to modulate transcription of specific target genes |
References for function | 17081979 |
E.C. number | |
Location of functional site(s) | |
Cellular location of function | nucleus |
Comments | |