| General Information |
| MoonProt ID | 4101 |
| First appeared in release | 4.0 |
| Name(s) | Phytosulfokine receptor 1 |
| UniProt ID | Q9ZVR7 |
| GO terms | "GO:0031347 regulation of defense response
GO:0045087 innate immune response
GO:0000166 nucleotide binding
GO:0001653 peptide receptor activity
GO:0001653 peptide receptor activity
GO:0001653 peptide receptor activity
GO:0004383 guanylate cyclase activity
GO:0004383 guanylate cyclase activity
GO:0004672 protein kinase activity
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0005515 protein binding
GO:0005515 protein binding
GO:0005515 protein binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0016829 lyase activity
GO:0106310 protein serine kinase activity
GO:0006182 cGMP biosynthetic process
GO:0009617 response to bacterium
GO:0031347 regulation of defense response
GO:0005886 plasma membrane" |
| Organisms for which functions have been demonstrated | Arabidopsis thaliana (Mouse-ear cress) |
| Sequence length | 1008.0 |
| FASTA sequence | ">sp|Q9ZVR7|PSKR1_ARATH Phytosulfokine receptor 1 OS=Arabidopsis thaliana OX=3702 GN=PSKR1 PE=1 SV=4
MRVHRFCVIVIFLTELLCFFYSSESQTTSRCHPHDLEALRDFIAHLEPKPDGWINSSSST
DCCNWTGITCNSNNTGRVIRLELGNKKLSGKLSESLGKLDEIRVLNLSRNFIKDSIPLSI
FNLKNLQTLDLSSNDLSGGIPTSINLPALQSFDLSSNKFNGSLPSHICHNSTQIRVVKLA
VNYFAGNFTSGFGKCVLLEHLCLGMNDLTGNIPEDLFHLKRLNLLGIQENRLSGSLSREI
RNLSSLVRLDVSWNLFSGEIPDVFDELPQLKFFLGQTNGFIGGIPKSLANSPSLNLLNLR
NNSLSGRLMLNCTAMIALNSLDLGTNRFNGRLPENLPDCKRLKNVNLARNTFHGQVPESF
KNFESLSYFSLSNSSLANISSALGILQHCKNLTTLVLTLNFHGEALPDDSSLHFEKLKVL
VVANCRLTGSMPRWLSSSNELQLLDLSWNRLTGAIPSWIGDFKALFYLDLSNNSFTGEIP
KSLTKLESLTSRNISVNEPSPDFPFFMKRNESARALQYNQIFGFPPTIELGHNNLSGPIW
EEFGNLKKLHVFDLKWNALSGSIPSSLSGMTSLEALDLSNNRLSGSIPVSLQQLSFLSKF
SVAYNNLSGVIPSGGQFQTFPNSSFESNHLCGEHRFPCSEGTESALIKRSRRSRGGDIGM
AIGIAFGSVFLLTLLSLIVLRARRRSGEVDPEIEESESMNRKELGEIGSKLVVLFQSNDK
ELSYDDLLDSTNSFDQANIIGCGGFGMVYKATLPDGKKVAIKKLSGDCGQIEREFEAEVE
TLSRAQHPNLVLLRGFCFYKNDRLLIYSYMENGSLDYWLHERNDGPALLKWKTRLRIAQG
AAKGLLYLHEGCDPHILHRDIKSSNILLDENFNSHLADFGLARLMSPYETHVSTDLVGTL
GYIPPEYGQASVATYKGDVYSFGVVLLELLTDKRPVDMCKPKGCRDLISWVVKMKHESRA
SEVFDPLIYSKENDKEMFRVLEIACLCLSENPKQRPTTQQLVSWLDDV" |
| Structure Information |
| PDB ID | "4Z63
4Z64" |
| Quaternary structure | NA |
| SCOP | |
| CATH | |
| TM Helix Prediction | 1 |
| DisProt Annotation | |
| Predicted Disorder Regions | |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | enzyme, kinase |
| References for function | Kwezi L, Ruzvidzo O, Wheeler JI, Govender K, Iacuone S, Thompson PE, Gehring C, Irving HR. The phytosulfokine (PSK) receptor is capable of guanylate cyclase activity and enabling cyclic GMP-dependent signaling in plants. J Biol Chem. 2011 Jun 24;286(25):22580-8. doi: 10.1074/jbc.M110.168823. Epub 2011 Apr 19. PMID: 21504901; PMCID: PMC3121402. |
| E.C. number | EC:4.6.1.2 |
| Location of functional site(s) | |
| Cellular location of function | transmembrane, with kinase domain in cytoplasmic domain |
| Comments | |
| Function 2 |
| Function description | enzyme, guanydylate cyclase |
| References for function | Kwezi L, Ruzvidzo O, Wheeler JI, Govender K, Iacuone S, Thompson PE, Gehring C, Irving HR. The phytosulfokine (PSK) receptor is capable of guanylate cyclase activity and enabling cyclic GMP-dependent signaling in plants. J Biol Chem. 2011 Jun 24;286(25):22580-8. doi: 10.1074/jbc.M110.168823. Epub 2011 Apr 19. PMID: 21504901; PMCID: PMC3121402. |
| E.C. number | EC:2.7.11.1 |
| Location of functional site(s) | |
| Cellular location of function | transmembrane, with GC domain in cytoplasmic domain |
| Comments | |