| General Information |
| MoonProt ID | 4117 |
| First appeared in release | 4.0 |
| Name(s) | Enolase |
| UniProt ID | V5T827 |
| GO terms | "GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity
GO:0016829 lyase activity
GO:0046872 metal ion binding
GO:0006096 glycolytic process
GO:0000015 phosphopyruvate hydratase complex" |
| Organisms for which functions have been demonstrated | Taenia solium (Pork tapeworm) |
| Sequence length | 433.0 |
| FASTA sequence | ">tr|V5T827|V5T827_TAESO Enolase OS=Taenia solium OX=6204 PE=2 SV=1
MSIQKIHARQIFDSRGNPTVEVDLTTAKGMFRAAVPSGASTGVHEAVELRDGDKNAYMGK
GVLNAVKNVNEVIAPALLKEKFIVTDQEKIDEFMIRLDGSPNKGKLGANAILGVSLAVCK
AGAAEKGVPLYRHIADLAGNKDVVLPVPSFNVLNGGSHAGNKLAMQEFMILPTGAKNFTE
AMKMGTEVYHHLKSVIKGKYGLDACNVGDEGGFAPNIQDNMEGLELLKTAIDRAGYTGKV
KIGMDVAASEFYQDGKYNLDFKNPAAAASSIVPGSKLAEIYLEMLSKYPIVSIEDPFDQD
DWAAWTAFNAKAGIQIVGDDLTVTNPERVQQAIDKKACNALLLKVNQIGSVTESIKACKM
SRAAGWGVMVSHRSGETEDSTIADIVVGLRTGQIKTGAPCRSERLAKYNQLLRIEEELGS
KAVYAGEHFRNPL" |
| Structure Information |
| PDB ID | NA |
| Quaternary structure | NA |
| SCOP | |
| CATH | |
| TM Helix Prediction | 0 |
| DisProt Annotation | |
| Predicted Disorder Regions | |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | enzyme, enolase, 2-phospho-D-glycerate => phosphoenolpyruvate + H2O Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. Carbohydrate degradation, glycolysis |
| References for function | _ |
| E.C. number | EC:4.2.1.11 |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | binds plasminogen |
| References for function | Ayón-Núñez DA, Fragoso G, Espitia C, García-Varela M, Soberón X, Rosas G, Laclette JP, Bobes RJ. Identification and characterization of Taenia solium enolase as a plasminogen-binding protein. Acta Trop. 2018 Jun;182:69-79. doi: 10.1016/j.actatropica.2018.02.020. Epub 2018 Feb 18. PMID: 29466706. |
| E.C. number | |
| Location of functional site(s) | |
| Cellular location of function | celll surface |
| Comments | |