| General Information |
| MoonProt ID | 426 |
| First appeared in release | 3.0 |
| Name(s) | Phosphotransferase, Gene: GLK4 |
| UniProt ID | Q59RR7 |
| GO terms | GO:0051156 glucose 6-phosphate metabolic process
GO:0006096 glycolytic process
GO:0005739 mitochondrion
GO:0001678 cellular glucose homeostasis
GO:0019158 mannokinase activity
GO:0008865 fructokinase activity
GO:0005829 cytosol
GO:0004340 glucokinase activity
GO:0004396 hexokinase activity
GO:0005536 glucose binding
GO:0005975 carbohydrate metabolic process
GO:0005524 ATP binding
GO:0016773 phosphotransferase activity, alcohol group as acceptor
GO:0016301 kinase activity
GO:0016740 transferase activity
GO:0000166 nucleotide binding
GO:0016310 phosphorylation
GO:0046835 carbohydrate phosphorylation |
| Organisms for which functions have been demonstrated | Candida albicans (yeast, a fungi, can cause candiadiasis) |
| Sequence length | 376 amino acids |
| FASTA sequence | >tr|Q59RR7|Q59RR7_CANAL Phosphotransferase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=GLK4 PE=3 SV=1
MSLSPKLEEIVSSIEKSFEIKDDFLVKATEYFIESMNVGLESPKPSKDVMPMIPTYVTSIPTGKEVGLYLAADLGGTNFRVCSIDLKGDHTFSMKQSKYRIPVDLMKAEKSNDLFGFLAKKVQSFLLENHSEACTAKNTEPLKLGFTFSFPVNQTALNRGTLIRWTKGFDIPDTVDRDVVELLQANLTILEVNVKVVAIANDTVGTLLTAAYSNDSAKTNRNTIIGCIFGTGTNGAYFESKIPKLSSSTGDNKGMVINTEWGSFDNGLKILPSTEFDEIVDSETANPGYHLFEKRISGMFLGEILRVALIHLFKKGLIFQELYKARGGSLPHRIEEPWLLDAEVLSYLQIDDSTDLKTSGLILQNVSQIGNQQGGT |
| Structure Information |
| PDB ID | NA |
| Quaternary structure | NA |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | Use FASTA sequence on the MFDp2 webserver.
moonID_426_uniID_Q59RR7 is 376 residues long, with 7 residues (1.86%) predicted as disordered.The protein has 1 short (< 30 residues) disorder segment and 0 long (>= 30 residues) disorder segments.
Segment 1 - Short (< 30 residues) disordered segment Segment is located between positions 370 and 376 in the sequence. The segment is 7 residues long (1.86 % of the total sequence length). |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | phosphotransferase |
| References for function | 21873635 |
| E.C. number | 2.7.1.- |
| Location of functional site(s) | NA |
| Cellular location of function | cytosol |
| Comments | NA |
| Function 2 |
| Function description | Binding of Plasma Proteins |
| References for function | 26636139 |
| E.C. number | NA |
| Location of functional site(s) | NA |
| Cellular location of function | NA |
| Comments | NA |