Protein Information

General Information
MoonProt ID438
First appeared in release3.0
Name(s)Fructose-bisphosphate aldolase, FBA1
UniProt IDQ9URB4
GO termsGO:0044416 induction by symbiont of host defense response GO:0030446 hyphal cell wall GO:0009277 fungal-type cell wall GO:0051701 interaction with host GO:0005886 plasma membrane GO:0009986 cell surface GO:0005515 protein binding
Organisms for which functions have been demonstratedCandida tropicalis (yeast, a fungi)
Sequence length359 amino acids
FASTA sequence>sp|Q9URB4|ALF_CANAL Fructose-bisphosphate aldolase OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=FBA1 PE=1 SV=2 MAPPAVLSKSGVIYGKDVKDLFDYAQEKGFAIPAINVTSSSTVVAALEAARDNKAPIILQ TSQGGAAYFAGKGVDNKDQAASIAGSIAAAHYIRAIAPTYGIPVVLHTDHCAKKLLPWFD GMLKADEEFFAKTGTPLFSSHMLDLSEETDDENIATCAKYFERMAKMGQWLEMEIGITGG EEDGVNNEHVEKDALYTSPETVFAVYESLHKISPNFSIAAAFGNVHGVYKPGNVQLRPEI LGDHQVYAKKQIGTDAKHPLYLVFHGGSGSTQEEFNTAIKNGVVKVNLDTDCQYAYLTGI RDYVTNKIEYLKAPVGNPEGADKPNKKYFDPRVWVREGEKTMSKRIAEALDIFHTKGQL
Structure Information
PDB IDNA
Quaternary structureNA
SCOPNA
CATHNA
TM Helix Predictionno TM helices
DisProt AnnotationNot in DisProt
Predicted Disorder RegionsUse FASTA sequence on the MFDp2 webserver. moonID_438_uniID_Q9URB4 is 359 residues long, with 0 residues (0.00%) predicted as disordered.The protein has 0 short (< 30 residues) disorder segments and 0 long (>= 30 residues) disorder segments.
Connections to Disease
OMIM ID
Function 1
Function descriptionGlycolytic enzyme; fructose bisphosphate aldolase
References for functionKozik, A.; Karkowska-Kuleta, J.; Zajac, D.; Bochenska, O.; Kedracka-Krok, S.; Jankowska, U.; Rapala-Kozik, M. Fibronectin-, vitronectin- and laminin-binding proteins at the cell walls of Candida parapsilosis and Candida tropicalis pathogenic yeasts. BMC Microbiol. 2015, 15, 197.
E.C. number4.1.2.13
Location of functional site(s)NA
Cellular location of functioncytoplasm
CommentsNA
Function 2
Function descriptionbinds fibronectin, vitronectin, and laminin
References for functionKozik, A., Karkowska-Kuleta, J., Zajac, D., Bochenska, O., Kedracka-Krok, S., Jankowska, U., Rapala-Kozik, M. Fibronectin-, vitronectin- and laminin-binding proteins at the cell walls of Candida parapsilosis and Candida tropicalis pathogenic yeasts. BMC Microbiol. 2015, 15, 197.
E.C. numberNA
Location of functional site(s)NA
Cellular location of functionNA
CommentsNA