Protein Information

General Information
MoonProt ID439
First appeared in release3.0
Name(s)Enolase 1, ENO1
UniProt IDC5M5Z6
GO termsGO:0019509 L-methionine salvage from methylthioadenosine GO:0000287 magnesium ion binding GO:0043874 acireductone synthase activity GO:0008652 cellular amino acid biosynthetic process GO:0016787 hydrolase activity GO:0046872 metal ion binding GO:0009086 methionine biosynthetic process
Organisms for which functions have been demonstratedCandida tropicalis (yeast, a fungi)
Sequence length240 amino acids
FASTA sequence>sp|C5M5Z6|ENOPH_CANTT Enolase-phosphatase E1 OS=Candida tropicalis (strain ATCC MYA-3404 / T1) OX=294747 GN=UTR4 PE=3 SV=1 MTIDTVILDIEGTVCPITFVKDTLFPYFLTKLPSILSSIEFPLSTSSSTNDDPIIQILKQLPESITISNESVFSYLKNLVDQDIKDPILKSLQGYIWEKGYEIGDLKAPIYKDSIKFIENFNKKIYIYSSGSIKAQILLFGHAEKDQESINLNPFLKGYFDITTAGFKNKSESYIKILNEINKSNDPSSVLFLSDNVNEVKSAIESGMNSYIVIRPGNAPLSDDDKSTYKTIHSLDELTL
Structure Information
PDB IDNA
Quaternary structureNA
SCOPNA
CATHNA
TM Helix Predictionno TM helices
DisProt AnnotationNot in DisProt
Predicted Disorder RegionsUse FASTA sequence on the MFDp2 webserver. moonID_439_uniID_C5M5Z6 is 240 residues long, with 0 residues (0.00%) predicted as disordered.The protein has 0 short (< 30 residues) disorder segments and 0 long (>= 30 residues) disorder segments.
Connections to Disease
OMIM ID
Function 1
Function descriptionEnolase 1
References for functionKozik, A.; Karkowska-Kuleta, J.; Zajac, D.; Bochenska, O.; Kedracka-Krok, S.; Jankowska, U.; Rapala-Kozik, M. Fibronectin-, vitronectin- and laminin-binding proteins at the cell walls of Candida parapsilosis and Candida tropicalis pathogenic yeasts. BMC Microbiol. 2015, 15, 197.
E.C. number4.2.1.11
Location of functional site(s)NA
Cellular location of functioncytoplasm
CommentsNA
Function 2
Function descriptionECM protein binding (fibronectin, vitronectin and laminin)
References for functionKozik, A.; Karkowska-Kuleta, J.; Zajac, D.; Bochenska, O.; Kedracka-Krok, S.; Jankowska, U.; Rapala-Kozik, M. Fibronectin-, vitronectin- and laminin-binding proteins at the cell walls of Candida parapsilosis and Candida tropicalis pathogenic yeasts. BMC Microbiol. 2015, 15, 197.
E.C. numberNA
Location of functional site(s)NA
Cellular location of functioncell surface
CommentsNA