Protein Information

General Information
MoonProt ID49
First appeared in release1.0
Name(s)GAPDH Glyceraldehyde 3-phosphate dehydrogenase Gene Name: gapB
UniProt IDF9UM10 (F9UM10_LACPL), Unreviewed
GO termsGO:0006006 glucose metabolic process GO:0055114 oxidation-reduction process GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity GO:0016491 oxidoreductase activity GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0050661 NADP binding GO:0051287 NAD binding
Organisms for which functions have been demonstratedLactobacillus plantarum (Gram positive bacterium)
Sequence length340
FASTA sequence>gi|334089837|gb|AEG64641.1| glyceraldehyde-3-phosphate dehydrogenase [Lactobacillus plantarum] MSVKIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNADVSATDDSIVVNGKNYRVYAEPQAQNIPWVKNDGVDFVLECTGFYTSKAKSQAHLDAGAKRVLISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNCLAPLAFFENKEFGIKVGTMTTIHAYTSTQMLLDGPVRGGNFRAARAAGVNTIPHSTGAAKALGLVIPELNGKLQGHAQRVGVVDGSLTELVAILDKKVTADEVNAAIKKHTEGNESFGYNDDEIVSSDVIGTTFGSIFDPTQTEVTSDGDNQLVKTVAWYDNEYGFTCQMVRTLLKFATL
Structure Information
PDB ID6IQM
Quaternary structure
SCOPNA
CATH3.30.360.10
TM Helix Predictionno TM helices
DisProt AnnotationNot in DisProt
Predicted Disorder Regions
Connections to Disease
OMIM ID
Function 1
Function descriptionGAPDH, enzyme Glyceraldehyde 3-phosphate dehydrogenase
References for function
E.C. number1.2.1.12
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionbinds mucin and Caco-2 cells
References for functionKinoshita H, Uchida H, Kawai Y, Kawasaki T, Wakahara N, Matsuo H,Watanabe M, Kitazawa H, Ohnuma S, Miura K, et al: Cell surface Lactobacillus plantarum LA 318 glyceraldehyde-3-phosphate dehydrogenase (GAPDH) adheres to human colonic mucin.J Appl Microbiol. 2008 Jun;104(6):1667-74. doi: 10.1111/j.1365-2672.2007.03679.x. Epub 2008 Jan 9. PMID: 18194256
E.C. numberN/A
Location of functional site(s)
Cellular location of functioncell surface
Comments