Protein Information

General Information
MoonProt ID704
First appeared in release4.0
Name(s)" Glutathione S-transferase"
UniProt IDM9ZT87
GO terms"GO:0004364 glutathione transferase activity GO:0016740 transferase activity"
Organisms for which functions have been demonstratedEquus caballus (Horse)
Sequence length222.0
FASTA sequence>tr|M9ZT87|M9ZT87_HORSE Glutathione S-transferase OS=Equus caballus OX=9796 GN=GSTA3 PE=1 SV=1 MAVKPMLHYFNGRGRMEPIRWLLAAAGVEFEETFIDTPEDFEKLKNDGSLMFQQVPMVEI DGMKLVQSRAILNYVAAKHNLYGKDIKERALIDMYIEGVADLNEMILLLPITPPAEKDAK IMLIKDRTTNRYLPAFEKVLKSHGEDYLVGNRLSRADIHLVELLYLVEELDPSLLTNFPL LKALKARISNLPTVKKFLQPGGARKPPGDEKSVEKSRKIFKF
Structure Information
PDB ID6ZJ9 6ZJC
Quaternary structureNA
SCOPNA
CATHNA
TM Helix Predictionno TM helices
DisProt Annotationnot in DisProt
Predicted Disorder RegionsPredicted disorder at N terminus (aa 1-4), and C terminus (aa 198-222)
Connections to Disease
OMIM ID
Function 1
Function descriptionenzyme, glutathione S-transferase
References for function"Lindström, H., Peer, S. M., Ing, N. H., and Mannervik, B. (2018). Characterization of Equine GST A3-3 as a Steroid Isomerase. J. Steroid Biochem. Mol. Biol. 178, 117–126. doi:10.1016/j.jsbmb.2017.11.011"
E.C. numberEC:2.5.1.18
Location of functional site(s)
Cellular location of functioncytoplasm
Comments
Function 2
Function descriptionenzyme, steroid isomerase
References for function"Lindström, H., Peer, S. M., Ing, N. H., and Mannervik, B. (2018). Characterization of Equine GST A3-3 as a Steroid Isomerase. J. Steroid Biochem. Mol. Biol. 178, 117–126. doi:10.1016/j.jsbmb.2017.11.011"
E.C. number
Location of functional site(s)
Cellular location of functioncytoplasm
Comments