| General Information |
| MoonProt ID | 82 |
| First appeared in release | 1.0 |
| Name(s) | Ornithine carbamoyltransferase
OTCase
Gene Name: argF_3
|
| UniProt ID | P0C0N1 |
| GO terms | GO:0006520 cellular amino acid metabolic process
GO:0006591 ornithine metabolic process
GO:0004585 ornithine carbamoyltransferase activity
GO:0016597 amino acid binding
GO:0016740 transferase activity
GO:0016743 carboxyl- or carbamoyltransferase activity
GO:0005737 cytoplasm |
| Organisms for which functions have been demonstrated | Staphylococcus epidermidis (Gram positive bacterium) |
| Sequence length | 333 aa |
| FASTA sequence | >sp|P0C0N1|OTC_STAES Ornithine carbamoyltransferase OS=Staphylococcus epidermidis (strain ATCC 12228) GN=argF PE=3 SV=1
MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLKNKNIALLFEKDSTRTRCAFEVAAHDQGAHVTYLGPTGSQMGKKETAKDTARVLGGMYDGIEYRGFSQRTVETLAQYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKEYADINFTYVGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTEELLNRCERIATENGGNILITDDIDKGVKDSDVIYTDVWVSMGEPDEVWQERLKLLKPYQVNQALLEKTGNPNVIFEHCLPSFHNAETKIGQQIYEKYGISEMEVTDDVFESKASVVFQEAENRMHTIKAVMVATLGEF
|
| Structure Information |
| PDB ID | closest is Vibrio at 65% amino acid sequence identity |
| Quaternary structure | |
| SCOP | NA |
| CATH | NA |
| TM Helix Prediction | no TM helices |
| DisProt Annotation | Not in DisProt |
| Predicted Disorder Regions | 1-4, 332-333 |
| Connections to Disease |
| OMIM ID | |
| Function 1 |
| Function description | Ornithine carbamoyltransferase, enzyme
Carbamoyl phosphate + L-ornithine => phosphate + L-citrulline |
| References for function | |
| E.C. number | 2.1.3.3 |
| Location of functional site(s) | |
| Cellular location of function | cytoplasm |
| Comments | |
| Function 2 |
| Function description | bind fibronectin |
| References for function | Hussain, M., G. Peters, G. S. Chhatwal, and M. Herrmann. 1999. A lithium chloride-extracted, broad-spectrum-adhesive 42-kilodalton protein of Staphylococcus epidermidis is ornithine carbamoyltransferase. Infect Immun. 1999 Dec;67(12):6688-90. PMID: 10569792 |
| E.C. number | N/A |
| Location of functional site(s) | |
| Cellular location of function | cell surface |
| Comments | |